Abstract
Case summary
A retrospective chart review was performed on 3 eyes of 3 patients who were without improvement and diagnosed with fungal keratitis by smear and culture on prior presentation with herpetic keratitis. Two cases were diagnosed with fungal keratitis, based on the results of culture. Fungal keratitis by Candida albicans was improved with antifungal agents, but a case caused by Fusarium species was more aggravated, regardless of antifungal agents. One case was improved by antifungal medications, which was diagnosed with fungal keratitis by the fungal hyphae manifestation on KOH preparation.
References
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Table 1.
Case | Age/sex | x Type of HSK* | Past history | Initial visual acuity | Initial treatment | Smear & Culture | Topical antifungal agent | Other treatment | Final visual acuity |
---|---|---|---|---|---|---|---|---|---|
1 | 73/F | Geographic epithelial keratitis, endotheliitis | DM† | 0.15 | Topical gancyclovir, Gatifloxacin, Oral acloclovir, Oral steroid | Candida albicans | Amphotericin-B, Voriconazole | − | 0.2 |
2 | 54/F | Dendritic epithelial keratitis | FC‡ 50 cm | Topical acyclovir, Gatifloxacin, Oral acloclovir | Fusarium species | Fluconazole, Amphotericin-B | AMT§ | HM | |
3 | 64/M | Geographic epithelial keratitis, endotheliitis | HTN∏, HSK | HM# | Topical acyclovir, Gatifloxacin, Oral acyclovir, Oral steroid | Fungal hypahe | Voriconazole | AMT | FC 30 cm |