Journal List > J Korean Ophthalmol Soc > v.50(6) > 1008587

Kim, Shim, and Seo: Neurilemoma of the Bulbar Conjunctiva: Report of One Case

Abstract

Purpose

To report one case of neurilemoma of the bulbar conjunctiva with a review of the relevant literature.

Case summary

A 15-year-old girl presented with a bulbar conjunctival mass in the right eye. There were no other medical or ophthalmologic problems. The patient wanted to remove the mass for cosmetic reasons. We performed an excisional biopsy and simple wound closure. The mass was composed of bipolar spindle shaped cells that were arranged in bundles and fascicles in dense fibrous tissue. Immunohistochemical staining for the S-100 protein was positive. Two months after mass excision, there was no evidence of recurrence.

Conclusions

We successfully treated a case of bulbar conjunctival neuriliemoma by simple excision.

References

1. Spencer WH. Ophthalmic Pathology: An Atlas and Textbook. 4th ed.Philadelphia: WB Saunders Co;1995. 1653–89. p. 2645–50.
2. McLaughlin ME, Pepin SM, Maccollin M, et al. Ocular JYPathologic Findings of Neurofibromatosis Type 2. Arch Ophthalmol. 2007; 125:389–94.
3. Kiratli H, Erkan K, Söylemezoglu F. Solitary orbital schwannomas: clinical, imaging, and surgical feature. J Fr Ophtalmol. 2007; 30:986–9.
4. Perry HD. Isolated episcleral neurofibroma. Ophthalmology. 1982; 89:1095–8.
crossref
5. Pineda R 2nd, Urban RC, Bellows AR, Jakobiec FA. Ciliary body neurilemmoma. Unusual clinical findings intimating the diagnosis. Ophthalmology. 1995; 102:918–23.
6. Lee JK, Song JS, Lee TW. A case of the ciliary body neurilemoma. J Korean Ophthalmol Soc. 1998; 39:1294–9.
7. Smith PA, Damato BE, Ko MK, Lyness RW. Anterior uveal neurilemmoma-a rare neoplasm simulating malignant melanoma. Br J Ophthalmol. 1987; 71:34–40.
crossref
8. Freedman SF, Elner VM, Donev I, et al. Intraocular neurilemmoma arising from the posterior ciliary nerve in neurofibromatosis, Pathologic findings. Ophthalmology. 1988; 95:1559–64.
9. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a male adult. Clin Experiment Ophthalmol. 2005; 33:412–3.
crossref
10. Yoon SW, Ahn BC. A case of orbital neurilemoma associated with neurofibromatosis. J Korean Ophthalmol Soc. 1999; 40:1993–7.
11. Kim JP, Lee MK, Park BI. A case of orbital neurilemoma. J Korean Ophthalmol Soc. 1986; 27:937–41.
12. Carroll GS, Haik BG, Fleming JC, et al. Peripheral nerve tumors of the orbit. Radiol Clin North Am. 1999; 37:195–202.
crossref
13. Grossniklaus HE, Green WR, Luckenbach M, Chan CC. Conjunctival lesions in the adults: a clinical and histopathologic review. Cornea. 1987; 6:78–116.
14. Ohshima K, Kitada M, Yamadori I. Neurilemoma of the bulbar conjunctiva. Jpn J Ophthalmol. 2007; 51:68–9.
crossref
15. Andreoli CM, Hatton M, Semple JP, et al. Perilimbal conjunctival schwannoma. Arch Ophthalmol. 2004; 122:388–9.
crossref
16. Charles NC, Fox DM, Avendano JA, et al. Conjunctival neurilemoma: report of 3 cases. Arch Ophthalmol. 1997; 115:547–9.
17. Le Marc'hadour F, Romanet JP, Fdili A, et al. Schwannoma of the bulbar conjunctiva. Arch Ophthalmol. 1996; 114:1258–60.
18. Shields CL, Shields JA. Tumors of the Conjunctiva and Cornea. Surv Ophthalmol. 2004; 49:3–24.
crossref
19. Jacobiec FA, Font RL, Zimmerman LE. Malignant peripheral nerve sheath tumors of the orbit: a clinicopathologic study of eight cases. Trans Am Ophthalmol Soc. 1985; 83:332–66.

Figure 1.
Photographs of the patient's right eye. (A) A relatively well demarcated 3×3 mm-sized pinkish mass in the bulbar conjunctiva. (B) Two months after excision of the bulbar conjunctival mass, conjunctival wound was healed without recurrence.
jkos-50-923f1.tif
Figure 2.
Light micrographs of the excised mass. (A) Hematoxylin and eosin-stained section showed spindled cells with oval, elongated nuclei arranged in fascicles (H&E, ×100). (B) The tumor cells are diffusely positive for S100 protein (immunohistochemical stain for S100, ×100).
jkos-50-923f2.tif
TOOLS
Similar articles