Various Treatments Using Invaluable Donor Cornea

Seong Taeck Kim; Young Chang Lee; Jun Heo; Seong Won Yang; Jae Woong Koh

doi:10.3341/jkos.2009.50.3.471

Journal List > J Korean Ophthalmol Soc > v.50(3) > 1008509

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Kim, Lee, Heo, Yang, and Koh: Various Treatments Using Invaluable Donor Cornea

Original Article

J Korean Ophthalmol Soc 2009;50(3):471-476.

Published online: 31 August 2009

DOI: https://doi.org/10.3341/jkos.2009.50.3.471

Various Treatments Using Invaluable Donor Cornea

Seong Taeck Kim, MD, Young Chang Lee, MD, Jun Heo, MD, Seong Won Yang, MD, Jae Woong Koh, MD, PhD

Department of Ophthalmology, Chosun University College of Medicine, Gwanju, Korea

Address reprint requests to Jae Woong Koh, MD, PhD, Department of Ophthalmology, Chosun University College of Medicine #588 Seoseok-dong, Dong-gu, Gwanju 501-717, Korea Tel: 82-62-220-3191, Fax: 82-62-225-9839, E-mail: clearcornea@paran.com

Received 23 April 2008 Accepted 4 November 2008

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To report cases of transplanting a donor's 2 corneas to 5 patients suffering from several corneal diseases.

Case summary

Two corneas were donated from a 66-year-old donor, who suffered from brain damage due to asphyxia, one hour after being pronounced dead by doctors. Two penetrating keratoplasties and 3 partial lamellar keratoplasties were performed for patients with corneal opacity, corneal ulcer and corneal perforation. After the procedure all grafts were stable.

Conclusions

Under the present circumstances of decreasing donations of corneas after death and the increasing demand for keratoplasty in Korea, the mutual cooperation among hospitals to treat more than one patient using one donated cornea is a method the authors believe can alleviate this situation.

Keywords: Corneal disease, Corneal transplantation, Donor cornea

References

1. Barron BA, Penetrating keratoplasty. The Cornea. 2nd ed.New York: Churchill Livingstone Inc;1998. p. 805–10.

2. Choi SH, Lee YW, Kim HM, et al. Epidemiologic studies of keratoplasty in Korea. J Korean Ophthalmol Soc. 2006; 47:538–547.

3. Terry MA, Ousley PJ. Small incision deep lamella endothelial keratoplasty. six-month results in the first prospective clinical study. Cornea. 2005; 24:59–65.

4. Melles GR, Eggink FA, Launder F, et al. A surgical technique for posterior lamella keratoplasty. Cornea. 1998; 17:618–25.

5. Terry MA, Ousley PJ. Endothelial replacement without surface corneal incisions or sutures. Cornea. 2001; 20:14–8.

6. Terry MA, Ousley PJ. Deep lamella endothelial keratoplasty in the first United States patients. Cornea. 2001; 20:239–43.

7. Uhm SL, Chung SK, Myung YW, Rhee SW. Clinical analysis of keratoplasty over a 23 year-time span. J Korean Ophthalmol Soc. 1991; 32:421–9.

8. Ha DW, Kim CK, Lee SE, et al. Penetrating keratoplasty results in 275 cases. J Korean Ophthalmol Soc. 2001; 42:20–29.

9. Eye bank association of America. 2002 eye banking statistical report. Washington, DC: Eye Bank Association of America;2003.

10. Means TL, Geroski DH, L'Hernault N, et al. The corneal epithelium after Optisol-GS storage. Cornea. 1996; 15:599–605.

11. Vajpayee RB, Sharma N, Jhanji V, et al. One donor cornea for 3 recipients. Arch Ophthalmol. 2007; 125:552–4.

Figure 1.

(A) Corneal opacity with stromal neovascularization was seen before penetrating keratoplasty by slit lamp examination. (B) Four months after a penetrating keratoplasty, graft tissue was clear and had no rejection sign.

Figure 2.

(A) Opaque and bullous cornea with neovascularization is seen by slit lamp examination. (B) One year after a penetrating keratoplasty, graft tissue was clear and had no rejection sign.

Figure 3.

(A) Aqueous leakage developed due to loose suture knots. (B) Loose sutures were removed and Histoacryl^® glue was applied. (C) After a Histoacryl^® glue removal, a partial superficial lamellar keratoplasty was performed. (D) Six months later, graft tissue was stable and central cornea was clear to see 20/20.

Figure 4.

(A) After a trauma of chestnuts bur, multiple dot-like white opacities were seen. Leakage was seen at 3 o'clock. (B) Forteen days after a partial superficial lamellar keratoplasty, graft tissue and anterior chamber was stable and no more leakage was seen.

Figure 5.

(A) The corneal perforation with iris incarceration was seen. (B) A partial superficial lamellar keratoplasty was performed. (C) Six months later, graft was well-epithelialized and in a stable state, but some localized fibro-vascular pannus developed.

TOOLS

Similar articles