Journal List > J Korean Ophthalmol Soc > v.50(2) > 1008485

Song and Park: A Case of Posterior Ischemic Optic Neuropathy and Abducens Nerve Palsy

Abstract

Purpose

To report a case of a patient with posterior ischemic optic neuropathy and abducens nerve palsy who responded to steroid therapy.

Case summary

A 47-year-old man visited our clinic with decreasing visual acuity and abduction limitation in his right eye, which suddenly started 4 days earlier. The best corrected visual acuity (BCVA) was 20/250 in the right eye and 20/20 in the left eye. Fundus examination showed normal in both eyes, and relative afferent pupillary defect was positive in the right eye. The visual field test showed a right central scotoma with inferior altitudinal field defect. In addition, the brain magnetic resonance imaging (MRI) was done. Orbit MRI, fluorescein angiography (FAG), and carotid ultrasonography results were normal. Therefore, the patient was diagnosed with non-arteritic posterior ischemic optic neuropathy. The systemic steroid therapy was started and tapered over a period of 5 weeks. At one month after treatment, the BCVA was 20/20 and abduction limitation in the right eye improved.

References

1. Jung JY, Kim JS. Comparison of optic disc appearance in anterior ischemic optic neuropathy and optic neuritis. J Korean Ophthalmol Soc. 2003; 44:157–61.
2. Kim DH, Hwang JM. Risk factors for Korean patients with anterior ischemic optic neuropathy. J Korean Ophthalmol Soc. 2007; 48:1527–31.
crossref
3. Park WC, Chang BL. Clinical features of anterior ischemic optic neuropathy. J Korean Ophthalmol Soc. 2003; 44:144–9.
4. Jun BK, Kim DS, Ko MK. Clinical features in anterior ischemic optic neuropathy. J Korean Ophthalmol Soc. 1999; 40:3460–7.
5. Hayreh SS. Posterior ischemic optic neuropathy: clinical features, pathogenesis, and management. Eye. 2004; 18:1188–206.
6. Hayreh SS. Ischemic optic neuropathy. Indian J Ophthalmol. 2000; 48:171–94.
crossref
7. Sadda SR, Nee M, Miller NR, et al. Clinical spectrum of posterior ischemic optic neuropathy. Am J Ophthalmol. 2001; 132:743–50.
crossref
8. Isayama Y, Takahashi T, Inoue M, et al. Posterior ischemic optic neuropathy III. Clinical Diagnosis. Ophthalmologica. 1983; 187:141–7.
9. Jeon C, Sa HS, Oh SY. Causes and natural course of the sixth cranial nerve palsy. J Korean Ophthalmol Soc. 2006; 47:1776–80.
10. Kim SS, Jin KH, Kim SM. Neuro-opthalmologic evaluation of the third, fourth, and sixth cranial nerve paralysis. J Korean Ophthalmol Soc. 1991; 32:283–8.
11. Park KH, Chang BL. The etiology and clinical feature of the third, fourth, and sixth cranial nerve palsy. J Korean Ophthalmol Soc. 1997; 38:1432–6.
12. Hayreh SS. Posterior ischemic optic neuropathy. Ophalmologica. 1981; 182:29–41.
crossref
13. Cullen JF, Por YM. Ischemic optic neuropathy: the Singapore scene. Singapore Med J. 2007; 48:281–6.
14. Smith KJ, Mcdonald WI. The pathophysiology of multiple sclerosis: the mechanisms underlying the production of symptoms and the natural history of the disease. Philos Trans R Soc Lond B Biol Sci. 1999; 354:1649–73.
crossref
15. Milea D, Napolitano M, Dechy H, et al. Complete bilateral horizontal gaze paralysis disclosing multiple sclerosis. J Neurol Neurosurg Psychiatry. 2001; 70:252–5.
crossref
16. Tan E, Kansu T. Bilateral horizontal gaze palsy in multiple sclerosis. J Clin Neuroophthalmol. 1990; 10:124–6.
17. Lee AG. Reversible loss of vision due to posterior ischemic optic neuropathy. Can J Ophthalmol. 1995; 30:327–9.
18. Rucker CW. Paralysis of the third, fourth, and sixth cranial nerves. Am J Ophthalmol. 1958; 46:787–94.
crossref
19. Rucker CW. The causes of paralysis of the third, fourth, and sixth cranial nerves. Am J Ophthalmol. 1966; 61:1293–8.
crossref
20. Rush JA, Young BR. Paralysis of cranial nerves III, IV, and VI: Cause and prognosis in 1000 cases. Arch Ophthalmol. 1981; 99:76–80.
21. Jacobson DM, McCanna TD, Layde PM. Risk factors for ischemic ocular motor nerve palsies. Arch Ophthalmol. 1994; 112:961–6.
crossref

Figure 1.
Nine cardinal gaze photographs. Patient shows limitation of abduction of the right eye in the right gaze position.
jkos-50-324f1.tif
Figure 2.
Disc photographs show normal optic discs in both eyes.
jkos-50-324f2.tif
Figure 3.
Fluorescein angiographs showing normal findings in the right eye.
jkos-50-324f3.tif
Figure 4.
Initial Humphrey visual field test (central 30-2 threshold) shows central scotoma and inferior altitudinal defect in the right eye.
jkos-50-324f4.tif
Figure 5.
The VEP shows a decrease in amplitude in the right eye.
jkos-50-324f5.tif
Figure 6.
Orbit MRI (A) T1W1 image, (B) T1W1 with enhancement image. MRI shows no mass lesion, nor abnormal enhancement in the optic nerve.
jkos-50-324f6.tif
Figure 7.
At one month after steroid therapy, the visual field test shows some inferior scotomas in the right eye.
jkos-50-324f7.tif
Figure 8.
Nine cardinal gaze photographs after steroid therapy. The patient does not show limitation of abduction in the right eye.
jkos-50-324f8.tif
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