Comparison of Measurement of Anterior Segment Parameters Between Scheimpflug Camera and Ultrasound Biomicroscopy

Yong-sik Park; Hyunseok Ahn; Na Rae Kim; Kyoung Tak Ma; Samin Hong; Gong Je Seong; Chan Yun Kim

doi:10.3341/jkos.2009.50.12.1847

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Park, Ahn, Kim, Ma, Hong, Seong, and Kim: Comparison of Measurement of Anterior Segment Parameters Between Scheimpflug Camera and Ultrasound Biomicroscopy

Original Article

J Korean Ophthalmol Soc 2009;50(12):1847-1852.

Published online: 7 September 2009

DOI: https://doi.org/10.3341/jkos.2009.50.12.1847

Comparison of Measurement of Anterior Segment Parameters Between Scheimpflug Camera and Ultrasound Biomicroscopy

Yong-sik Park, MD¹, Hyunseok Ahn, MD¹, Na Rae Kim, MD¹, Kyoung Tak Ma, MD², Samin Hong, MD¹, Gong Je Seong, MD, PhD¹, Chan Yun Kim, MD, PhD¹

¹The Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea

²Siloam Eye Hospital, Seoul, Korea

Address reprint requests to Chan Yun Kim, MD, PhD, Department of Ophthalmology, Severance Hospital, College of Medicine, Yonsei University #134 Sinchon-dong, Seodaemun-gu, Seoul 120-752, Korea Tel: 82-2-2228-3570, Fax: 82-2-312-0541, E-mail: kcyeye@yuhs.ac

Received 4 May 2009 Accepted 17 August 2009

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the clinical reliability of Pentacam^® by comparing anterior chamber parameters measured by Oculus Pentacam system (Oculus Inc., Germany) and Hi-scan ultrasound biomicroscopy (OPTIKON 2000, Rome, Italy) in primary angle closure (PAC) and normal patients.

Methods

A prospective study was performed from June 2006 to January 2007. Fifty-one eyes in 26 primary angle-closure patients and 39 eyes in 20 normal control patients, for a total of 90 eyes of 46 patients were recruited from glaucoma outpatient clinics. The correlation and agreement of both measurements of anterior chamber depth and anterior chamber angle measured by UBM and Pentacam^® were calculated. Sensitivity and specificity of each tool were also compared and the diagnostic value of angle closure was examined.

Results

Anterior chamber depth measured by UBM and Pentacam^® showed strong correlation in the normal control group (r=0.821) and PAC group (r=0.957). Anterior chamber angle showed moderate correlation in the normal control group (r=0.523) and PAC group (r=0.456) while good agreement was also observed. In diagnosing angle closure, anterior chamber measurements appear similar in UBM and Pentacam^® using the ROC curve (AUC of UBM, 0.942; AUC of Pentacam^®, 0.931).

Conclusions

Pentacam^® shows high to moderate correlation of anterior chamber measurements and good agreement compared with UBM. Pentacam^® shows similar ability in diagnosing angle closure compared with UBM and thus is expected to be a good tool in diagnosing angle closure.

Keywords: Anterior chamber angle, Anterior chamber depth, Pentacam, Primary angle-closure glaucoma (PACG), Ultrasound biomicroscope (UBM)

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Figure 1.

Trabeculariris angle (TIA) depicted on an ultrasound biomicroscopic (UBM) image of a normal eye.

Figure 2.

Bland-Altmann plots of anterior biometry measurements between ultrasound biomicroscopy (UBM) and Pentacam^®. Solid line: 95% confidence interval of the difference between the methods.

Figure 3.

Comparison of ultrasound biomicroscopy (UBM) and Pentacam^® measurements of the anterior chamber angle for the diagnosis of primary angle-closure or primary angle-closure glaucoma.

Table 1.

Characteristics of the study population

	Age (yrs)	Sex
	Age (yrs)	M	F
Normal (n=20)	46.7±21.2	10	10
Angle closure glaucoma (n=26)	70.5±7.4	21	5

Table 2.

Correlation analysis between ultrasound biomicroscopy (UBM) and Pentacam^® measurements of anterior chamber depth of normal and primary angle-closure patients

	Anterior chamber depth (mm)		Pearson's correlation coefficient
	UBM	Pentacam^®	Coefficeint	p-value^*
Normal	2.74±0.63	3.00±0.60	0.821	<0.01
Patients	1.70±0.27	1.80±0.30	0.957	<0.01

^* In normal and primary angle-closure patients, anterior chamber depth was measured by ultrasound biomicroscopy (UBM) and Pentacam

^® Pearson's correlation coefficient was computed between the two groups (p<0.05).

Table 3.

Correlation analysis between ultrasound biomicroscopy (UBM) and Pentacam^® measurements of anterior chamber angle of normal and primary angle-closure patients

	Anterior chamber angle (°)		Pearson's correlation coefficient
	UBM	Pentacam^®	Coefficeint	p-value^*
Normal	38.00±7.00	37.80±8.82	0.523	0.01
Patients	24.10±5.50	21.38±5.01	0.456	0.01

^* In normal and primary angle-closure patients, anterior chamber angle was measured by ultrasound biomicroscopy (UBM) and Pentacam

^® Pearson's correlation coefficient was computed between the two groups (p<0.05).

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