A Case of Primary Mucinous Adenocarcinoma on Skin of The Lateral Canthus

Seong Min Hong; Sang Duck Kim; Ki Jung Yun

doi:10.3341/jkos.2009.50.10.1582

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Hong, Kim, and Yun: A Case of Primary Mucinous Adenocarcinoma on Skin of The Lateral Canthus

Original Article

J Korean Ophthalmol Soc 2009;50(10):1582-1585.

Published online: 3 August 2009

DOI: https://doi.org/10.3341/jkos.2009.50.10.1582

A Case of Primary Mucinous Adenocarcinoma on Skin of The Lateral Canthus

Seong Min Hong, MD¹, Sang Duck Kim, MD¹, Ki Jung Yun, MD²

¹Department of Ophthalmology, Wonkwang University School of Medicine and Institute of Wonkwang Medical Science, Iksan, Korea

²Department of Pathology, Wonkwang University School of Medicine and Institute of Wonkwang Medical Science, Iksan, Korea

Address reprint requests to Sang Duck Kim, MD Department of Ophthalmology, Wonkwang University School of Medicine #344-2 Sinyong-dong, Iksan 570-711, Korea Tel: 82-63-859-1383, Fax: 82-63-855-1801, E-mail: sangduck@wonkwang.ac.kr

Received 21 April 2009 Accepted 30 June 2009

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To report a rare case of primary mucinous adenocarcinoma arising from a sweat gland in the eyelid.

Case summary

A 68-year-old male presented to our hospital with a painless, superficial nodular lesion over the skin of the right lateral canthus that had slowly grown over the past two years. The patient had a history of surgical excision for three nodular lesions at the same site 5 years ago, and an excisional biopsy was mucinous adenocarcinoma with a positive margin. A systemic evaluation, including whole-body Positron Emission Tomography scan (PET), chest computerized tomography, gastro-intestinal endoscopy, and colonoscopy, revealed no other abnormal lesions. Therefore, the eyelid lesion was considered a primary mucinous adenocarcinoma of the skin.

Conclusions

Primary mucinous adenocarcinoma of the eyelid can rarely metastasize. Therefore, a systemic examination is warranted to discriminate primary and metastatic adenocarcinoma and also to monitor the long-term follow-up for the evaluation of local recurrence.

Keywords: Lateral Canthus, Primary mucinous adenocarcinoma, Sweat gland

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Figure 1.

Recurrent nodular mass on the right lateral canthus, 5 years after initial surgical resection of mucinous adenocarcinoma in the same location.

Figure 2.

The tumor was divided into numerous compart-ments. In each compartment, large mucin pools contain the tumor cells (H&E, ×100).

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