Comparative Study of Two Aspheric, Aberration-Free Intraocular Lenses in Cataract Surgery

Sang Yeop Lee; Jae Lim Chung; Jin Pyo Hong; Kyoung Yul Seo; Eung Kweon Kim; Tae Im Kim

doi:10.3341/jkos.2009.50.10.1520

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Lee, Chung, Hong, Seo, Kim, and Kim: Comparative Study of Two Aspheric, Aberration-Free Intraocular Lenses in Cataract Surgery

Original Article

J Korean Ophthalmol Soc 2009;50(10):1520-1526.

Published online: 3 August 2009

DOI: https://doi.org/10.3341/jkos.2009.50.10.1520

Comparative Study of Two Aspheric, Aberration-Free Intraocular Lenses in Cataract Surgery

Sang Yeop Lee, MD, Jae Lim Chung, MD, Jin Pyo Hong, MD, Kyoung Yul Seo, MD, Eung Kweon Kim, MD, PhD, Tae Im Kim, MD

The Institute of Vision Research, Department of Ophthalmology, Yonsei University, College of Medicine, Seoul, Korea

Address reprint requests to Tae Im Kim, MD Department of Ophthalmology, Yonsei University College of Medicine #134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Korea Tel: 82-2-2228-3570, Fax: 82-2-312-0541, E-mail: tikim@yuhs.ac

Received 25 February 2009 Accepted 7 July 2009

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To compare clinical outcomes of aberration-free MI60 intraocular lens (IOL) in microincision cataract surgery and an aberration-free intraocular lens, Akreos AO in conventional cataract surgery.

Methods

Patients were randomly assigned to two IOL groups, and were examined preoperatively, and at one and three months postoperatively. The performed ophthalmologic evaluation included best corrected visual acuity (BCVA), measurement of refractive error, corneal astigmatism, and surgically induced astigmatism. The spherical, total, and higher-order aberration analysis of the two groups were assessed at one month and three months after operation.

Results

MI60 IOL group provided significantly less corneal astigmatism (p=0.020) one month after operation, compared to Akreos AO group. The MI60 group also showed significantly less surgically-induced astigmatism at one month (p=0.021) and three months postoperatively (p=0.043). There was no statistically significant difference in the spherical, higher-order, and total aberration between the two groups at one and three months after operation.

Conclusions

MI60 IOL group resulted in less corneal astigmatism and surgically induced corneal astigmatism than the Akreos AO IOL group. There was no statistically significant difference in spherical, higher-order, and total aberrations between the two groups.

Keywords: Aberration free intraocular lens, Corneal astigmatism, MI60, Spherical aberration, Surgically induced astigmatism

References

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Figure 1.

The appearance of intraocular lenses.

Table 1.

Characteristics of the two IOL in the study

IOL^* Characteristics	Akreos AO	MI60
Type	1 piece	1 piece
Optic material	26% Acrylic material	26% Hydrophilic acrylic
Refractive index	1.458	1.458
Optic shape	Biconvex aspheric anterior and posterior	Biconvex aspheric anterior and posterior
Haptics shape	One-piece	One-piece
	10˚ average angulation	0˚ average angulation

^* Intraocular lens.

Table 2.

Preoperative and postoperative visual acuity and refraction, corneal astigmatism, surgically induced astigmatism of Akreos AO

	UCVA^*	BCVA^†	SE^‡	Cor. Astig.^§	SIA^П
Pre op.	0.44±0.27	0.56±0.33	0.13±1.87	0.62±0.28
Post op. 1M	0.66±0.28	0.86±0.22	-0.28±0.43	1.05±0.36	1.06±0.75
Post op. 3M	0.78±0.25	0.94±0.15	-0.33±0.76	0.87±0.44	0.93±0.55
p-value	0.006	0.004	0.262	0.010	0.620

^* Uncorrected visual acuity;

^† Best corrected visual acuity;

^‡ Spherical equivalent;

^§ Corneal astigmatism;

^П Surgically induced astigmatism.

Table 3.

Preoperative and postoperative visual acuity and refraction, corneal astigmatism, surgically induced astigmatism of MI60

	UCVA^*	BCVA^†	SE^‡	Cor. Astig.^§	SIA^П
Pre op.	0.36±0.25	0.57±0.26	-0.15±1.72	0.67±0.39
Post op. 1M	0.65±0.16	0.91±0.10	-0.85±0.53	0.63±1.85	0.58±0.33
Post op. 3M	0.58±0.18	0.93±0.08	-0.92±0.64	0.71±0.47	0.59±0.37
p-value	0.000^#	0.000^#	0.028	0.921	0.970

^* Uncorrected visual acuity;

^† Best corrected visual acuity;

^‡ Spherical equivalent;

^§ Corneal astigmatism;

^П Surgically induced astigmatism;

^# p<0.05.

Table 4.

Comparison of postoperative corneal astigmatism, surgically induced astigmatism, difference of corneal astigmatism

	Akreos AO	MI60	p-value
Cor. Astig^*
Post op 1M	1.05±0.36	0.63±0.36	0.020
Post op 3M	0.87±0.44	0.71±0.47	0.254
Cor. Astig Diff.^†
Post op 1M	0.43±0.44	0.06±0.36	0.005
Post op 3M	0.25±0.54	-0.02±0.51	0.314
SIA^‡
Post op 1M	1.06±0.75	0.58±0.33	0.021
Post op 3M	0.93±0.55	0.59±0.37	0.043

^* Corneal astigmatism;

^† Difference of corneal astigmatism (Post op corneal astigmatism – Pre op corneal astigmatism);

^‡ Surgically induced astigmatism.

Table 5.

Comparison of aberrations in each study group

	Akreos AO 1M	MI60 1M	Akreos AO 3M	MI60 3M	p-value (1M/3M)
RMS total^*	1.73±0.65	2.41±1.33	1.43±0.62	2.91±1.82	0.117/0.012
Sph A^†	0.25±0.21	0.09±0.28	0.17±0.27	-0.07±0.75	0.067/0.117
(entire)
SphA^†	-0.02±0.2	-0.06±0.35	-0.02±0.24	-0.27±0.75	0.789/0.079
(int. optics^§)
SphA^†	0.27±0.09	0.25±0.19	0.22±0.11	0.21±0.14	0.509/0.682
(Cornea)
HOtotal^‡	1.00±0.42	1.05±0.84	0.96±0.51	1.60±1.56	0.682/0.762
Int. optics^§
Trefoil6	0.05±0.49	0.33±0.51	0.15±0.57	0.40±0.56	0.155/0.215
Trefoil9	-0.48±0.47	-0.01±0.37	-0.18±0.47	-0.04±0.56	0.020/0.307
Coma7	0.10±0.45	0.15±0.75	0.02±0.52	-0.16±1.17	0.343/0.929
Coma8	0.08±0.39	0.01±0.20	0.05±.026	0.12±0.67	0.190/0.682
Entire
Trefoil6	0.05±0.37	0.22±0.43	0.10±0.35	0.25±0.49	0.290/0.361
Trefoil9	-0.15±0.39	0.03±0.22	-0.02±0.45	-0.07±0.63	0.190/0.762
Coma7	0.08±0.29	0.17±0.57	-0.04±0.27	-0.04±1.12	0.343/0.509
Coma8	0.05±0.38	-0.03±0.18	0.04±0.27	0.07±0.69	0.244/0.762
Cornea
Trefoil6	0.00±0.18	-0.05±0.27	-0.06±0.29	-0.11±0.21	0.605/0.325
Trefoil9	0.33±0.29	0.15±0.15	0.16±0.21	0.10±0.15	0.062/0.556
Coma7	-0.01±0.21	0.11±0.29	-0.04±0.28	0.10±0.18	0.290/0.202
Coma8	0.05±0.23	0.03±0.18	0.00±0.22	0.00±0.16	0.789/0.762

^* Root mean square of total aberrations;

^† Spherical aberration;

^‡ Root mean square of total higher order aberrations (3rd to 6th order);

^§ Internal optics.

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