Effectiveness for Intralesional Triamcinolne Acetonide Injections for Chalazia in Pediatric Patients

Ju Hong Park; Jun Hyuk Son

doi:10.3341/jkos.2009.50.9.1295

Journal List > J Korean Ophthalmol Soc > v.50(9) > 1008352

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Park and Son: Effectiveness for Intralesional Triamcinolne Acetonide Injections for Chalazia in Pediatric Patients

Original Article

J Korean Ophthalmol Soc 2009;50(9):1295-1300.

Published online: 7 September 2009

DOI: https://doi.org/10.3341/jkos.2009.50.9.1295

Effectiveness for Intralesional Triamcinolne Acetonide Injections for Chalazia in Pediatric Patients

Ju Hong Park, MD, Jun Hyuk Son, MD

Department of Ophthalmology, Yeungnam university College of Medicine, Daegu, Korea

Address reprint requests to Jun Hyuk Son, MD Department of Ophthalmology, Yeungnam university College of Medicine #317-1 Daemyeong-dong, Nam-gu, Daegu 705-717, Korea Tel: 82-53-620-3444, Fax: 82-53-626-5936, E-mail: sjh@med.yu.ac.kr

Received 13 April 2009 Accepted 4 August 2009

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the effectiveness of intralesional triamcinolone acetonide injection for chalazia in pediatric patients.

Methods

We performed a retrospective chart review of 58 patients (70 lesions) under fifteen years of age and 40 patients (50 lesions) aged fifteen and over, who underwent intralesional triamcinolone acetonide injections and performed followups for at least three months between January 2007 and October 2008. Data regarding age, sex, lesion size, location, number of injections, treatment success, surgery, and complications were evaluated.

Results

Cumulative treatment success of TA was 64.3% with the first injection, 82.9% with a second injection, and 88.6% with a third injection in patients under fifteen years of age. The average number of TA injections was 1.67±1.03 in primary chalazia and 1.48±0.87 in recurrent chalazia, while the cumulative treatment success until third TA injection was 89.8% in primary chalazia and 85.7% in recurrent chalazia inpatients under fifteen years old. The average number of TA injections was 1.95±1.18 in primary chalazia and 1.80±1.14 in recurrent chalazia, while the cumulative treatment success until the third TA injection was 82.5% in primary chalazia and 70.0% in recurrent chalazia in patients aged fifteen and over. No complications were noted with TA injections.

Conclusions

Intralesional triamcinolone acetonide injection in chalazia is an effective and safe treatment in pediatric patients.

Keywords: Chalazion, Intralesional injection, Triamcinolone acetonide

References

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Figure 1.

Patient with a left lower lid chalazion (A) and remission after intralesional triamcinolone acetonide injection (B). Patient with both upper lid chalazion (C) and remission after intralesional triamcinolone acetonide injection (D).

Table 1.

Patient characteristics

Characteristics	Age
Characteristics	<15 years	≥15 years
No. of lesions (patients)	70 (58)	50 (40)
Gender
Male	30	21
Female	28	19
Age (years)	4.14±3.09	37.8±15.1
Location
Right upper lid	20	14
Right lower lid	18	12
Left upper lid	16	13
Left lower lid	16	11

Table 2.

Average number and cummulative treatment success of intralesional triamcinolone acetonide injections in chalazia

Characteristics	Age groups		p-value
Characteristics	< 15 years	≥ 15 years	p-value
No. of lesions	70	50
Average number of TA^∗ injections	1.61±0.98	1.92±1.16	0.122^†
Cummulative success by TA injection number
1 ^st	45 (64.3%)	27 (54.0%)
2 ^nd	58 (82.9%)	34 (68.0%)
3 ^rd	62 (88.6%)	40 (80.0%)	0.195^‡

^∗ Triamcinolone acetonide;

^† Independent sample t test;

^‡ Chi-square test.

Table 3.

Average number and cummulative treatment success of intralesional triamcinolone acetonide injections in patient under fifteen

Characteristics	groups		p-value
Characteristics	Primary chalazia	Recurrent chalazia	p-value
No. of lesions	49	21
Average number of TA^∗ injections	1.67±1.03	1.48±0.87	0.445^†
Cummulative success by TA injection number
1 ^st	30 (61.2%)	15 (71.4%)
2 ^nd	40 (81.6%)	18 (85.7%)
3 ^rd	44 (89.8%)	18 (85.7%)	0.689^‡

^∗ Triamcinolone acetonide;

^† Independent sample t-tes;

^‡ Fisher exact test.

Table 4.

Average number and cummulative treatment success of intralesional triamcinolone acetonide injections in primary chalazia

Characteristics	Age groups		p-value
Characteristics	<15 years	≥15 years	p-value
No. of lesions	49	40
Average number of TA^∗ injections	1.67±1.03	1.95±1.18	0.240^†
Cummulative success by TA injection number
1 ^st	30(61.2%)	21(52.5%)
2 ^nd	40(81.6%)	27(67.5%)
3 ^rd	44(89.8%)	33(82.5%)	0.362^‡

^∗ Triamcinolone acetonid;

^† Independent sample t test;

^‡ Fisher exact test.

Table 5.

Average number and cummulative treatment success of intralesional triamcinolone acetonide injections in recurrent chalazia

Characteristics	Age groups		p-value
Characteristics	<15 years	≥15 years	p-value
No. of lesions	21	10
Average number of TA^∗ injections	1.48±0.87	1.80±1.14	0.388^†
Cummulative success by TA injection number
1 ^st	15 (71.4%)	6 (60.0%)
2 ^nd	18 (85.7%)	7 (70.0%)
3 ^rd	18 (85.7%)	7 (70.0%)	0.358^‡

^∗ Triamcinolone acetonide;

^† Independent sample t test;

^‡ Fisher exact test.

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