Abstract
Purpose:
To report a case of acute transient myopic shift in a patient with fever of unknown origin.
Case summary:
A 31-year-old woman without a history of any ophthalmic problems presented with a sudden onset of bilateral blurred vision. She was admitted with the diagnosis of fever of unknown origin (FUO). Ophthalmic examination revealed a visual acuity of 0.06 in the right eye and 0.1 in the left eye. A myopic shift of 3.12 diopters (D) and 2.25D was noted in the right and left eyes, respectively. Retinal folds and choroidal thickening accompanied the myopic shift. On the third day after onset, visual acuity had decreased even more. Myopic shift increased to 4.87D in the right eye and 4.50D in the left eye. At the same time, the depth of the anterior chamber maximally decreased and the thickness of the lens was maximally increased. One week later, the myopic shift was normalized to emmetropia. The depth of the anterior chamber and the thickness of the lens also normalized as the fever subsided.
References
1. Saari KM, Luoto S. Ophthalmological findings in nephropathia epidemica in Lapland. Acta Ophthalmol. 1984; 62:235–43.
2. Bloch RS, Henkind P. Ocular manifestations of endocrine and metabolic diseases. Tasman W, Gold D, editors. Duane's clinical textbook of ophthalmology. Philadelphia: Lippincott;1992. 5:chap. 21.
3. Craig JE, Ong TJ, Louis DL, Wells JM. Mechanism of topiramate− induced acute-onset myopia and angle closure glaucoma. Am J Ophthalmol. 2004; 137:193–5.
5. Pärssinen O, Klemetti A, Rossi-Rautiainen E, Forslund T. Oph-thalmic manifestations of epidemic nephropathy. Acta Ophthalmol. 1993; 71:114–6.
7. Bovino JA, Marcus DF. The mechanism of transient myopia induced by sulfonamide therapy. Am J Ophthalmol. 1982; 94:99–102.
8. Kim SW, Seo SG, Her J, et al. Two Cases of Topiramate-induced Acute Myopia. J Korean Ophthalmol Soc. 2008; 49:1033–40.
9. Kontkanen M, Puustjärvi T, Lähdevirta J. Myopic shift and its mechanism in nephropathia epidemiaca or puumala virus infection. Br J Ophthalmol. 1994; 78:903–6.
10. Hwang HS, Kim DH. Transient Myopia with Severe Chemosis Associated with Systemic Lupus Erythematosus. J Korean Ophthalmol Soc. 2007; 48:1445–8.
11. Petersdorf RG, Beeson PB. Fever of unexplained origin: report on 100 cases. Medicine. 1961; 43:1–30.
12. Larson EB, Featherstone HJ, Petersdorf RG. Fever of undeter-mined origin: diagnosis and follow-up of 105 cases, 1970-1980. Medicine. 1982; 61:269–92.
13. Kontkanen M, Puustjärvi T, Kauppi P, Lähdevirta J. Ocular characteristics in nephropathia epidemica or puumala virus infection. Acta Ophthalmol Scand. 1996; 74:621–5.