Journal List > J Korean Ophthalmol Soc > v.49(5) > 1008275

Lee, Moon, Park, and Choi: A Case of Anterior Fibrovascular Membrane After Intraocular Lens Implantation in Congenital Aniridia

Abstract

Purpose

To report a case of an anterior fibrovascular membrane following cataract extraction and intraocular lens implantation in a patient with congenital aniridia.

Case summary

A 13-year-old girl presented with congenital aniridia and cataracts in both eyes. She underwent cataract extraction by phacoemulcification with intraocular lens implantation. Six months after cataract surgery, a progressive anterior chamber fibrovascular membrane was noted in both intraocular lens and rudimentary iris. Surgical excision of the fibrovascular membrane was performed, but there was recurrence after five weeks in both eyes. Subsequent surgical intervention on both eyes involved intraocular lens explantation combined with membranectomy to prevent recurrence and phthisis. Surgical findings indicated that the fibrovascular membrane involved the retrolenticular space, and histopathological evidence indicated that the extensive fibrotic tissue originated from the root of the rudimentary iris.

Conclusions

Patients with congenital aniridia should be monitored carefully for the development of intraocular fibrosis after intraocular lens implantation. If a fibrovascular membrane is noted, early surgical intervention is recommended, and the explantation of the intraocular lens should be considered during surgical intervention to prevent recurrence and complications.

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Figure 1.
(A) Preoperative microscopic findings after intraocular lens implantation. (B) Progressive formation of fibrovascular membrane (F) with extension of the membrane anteriorly in the anterior chamber. C = cornea: I = black-diaphragm intraocular lens. (C) Intraocular lens (I) explantation combined with fibrovascular membrane removal. (D) Microscopic findings after fibrovascular membrane removal.
jkos-49-835f1.tif
Figure 2.
Light microscopy of fibrous membrane shows dense hypocellular fibrous membrane (F) with mild vascularization. H = lens haptic imprint; I = iris root. (Hematoxylin and eosin stain; original magnification, (A) ×20; (B) ×40).
jkos-49-835f2.tif
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