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Abstract
Purpose
To determine whether there are significant differences between the retinal thicknesses of the macular area in eyes of healthy Koreans compared with normative data using OCT3 (version 4.0).
Methods
The study was performed in 111 eyes of 71 adults between the ages of 20 and 69 with corrected vision of 0.8 or greater and no systemic or ocular disease. The subject group was designed to have a similar age distribution to that of normative data. An OCT3 fast macular map was used to measure macular thickness. The results were further analyzed and compared with the normative data.
Results
The overall results from the subject group were similar to the normative data. However, the nasal parts of the outer ring were thicker than the normative data and the temporal parts of the outer ring were thinner (p<.0001). When each age group was compared, the thickness of the superior part of the inner ring and the nasal part of the inner and outer rings were thicker than the normative data in the age groups of twenties and thirties (p<.05). For the nasal parts of outer ring, the macula were thicker by OCT examination than the normative data in 25.2% of subjects, although they were clinically normal.
References
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Figure 1.
Sample OCT3 display of diabetic macular edema patient with normative data. It displays the macular normative database information in the form of clinically useful fast macular map and chart. Colored bands demonstrate the normal distribution of macular thickness measurements.
Figure 2.
An analysis of the spread of macular thickness by OCT3 normative data in healthy Korean. At first the population was divided in age categories, and then five sub‐ groups were made according to color‐ code of the normative data. Color-code of the normative data was divided in following percentile categories: more than 99% as very thick, 95∼99% as thick, 5∼95% as normal, 1∼ 5% as thin, and less than 1% as very thin. Number of eyes was presented in each macular area of each sub-group. Some cases represented abnormal, even though patients' macula was normal clinically. * 1 mm=1 mm central ring; †3=3 mm inner ring; ‡6=6 mm outer ring; § tem=temporal; ∏ sup=superior; ＃ nas=nasal; ** inf=inferior.
Figure 4.
Comparison of healthy Korean macular thickness between male and female. * 1 mm=1 mm central ring; †3=3 mm inner ring; ‡6=6 mm outer ring; § tem=temporal; ∏ sup=superior; ＃ nas=nasal; ** inf=inferior.
Table 1.
Subject distribution by age
Table 2.
Comparison between macular thickness of healthy Korean and normative data of OCT3
| | | Present data (µm) | Normative data (µm) | p-value |
|---|---|---|---|---|
| Central ring | | 198.7±16.5 | 203.5±21.5 | .0818 |
| Inner ring | Superior | 277.1±16.1 | 269.5±16.1 | .0579 |
| | Inferior | 265.3±19.2 | 271.5±15.5 | .0981 |
| | Nasal | 276.3±16.2 | 268.5±17.3 | .0622 |
| | Temporal | 261.5±15.3 | 267.0±16.4 | .1054 |
| | Mean | 270.0±15.0 | 269.1±15.2 | .5412 |
| Outer ring | Superior | 240.4±13.2 | 231.5±14.8 | .0746 |
| | Inferior | 237.9±14.9 | 231.5±14.8 | .2823 |
| | Nasal | 264.7±13.9 | 236.0±23.0 | <.0001* |
| | Temporal | 224.6±13.0 | 237.5±23.3 | <.0001* |
| | Mean | 241.9±12.2 | 233.8±14.5 | .0612 |
Table 3.
Macular thickness measurements in healthy eyes reported in previous studies using OCT
Table 4.
Macular thickness measurements in healthy korean eyes reported in previous studies using OCT
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