Abstract
Purpose
To evaluate the correlation between the degree of serous fluid and best corrected visual acuity at the first visit in central serous chorioretinopathy using optical coherence tomography.
Methods
Retrospective analysis was performed for 30 eyes of 30 patients with central serous chorioretinopathy. Cross-sectional retinal images through the center of the fovea were obtained from all eyes by optical coherence tomography. The height, sectional area, and the tangent of theta (tan θ) were estimated. They were statistically analyzed and correlated with best corrected visual acuity.
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Figure 1.
(A) The fundus photograph shows an grayish-white lesion to the fovea. (B) Fluorescein angiogram shows a detachment of neurosensory retina with dye leakage in the area of grayish-white lesion. (C) A tomographic sectional image of the lesion.
![jkos-49-282f1.tif](/upload/SynapseXML/0035jkos/thumb/jkos-49-282f1.gif)
Figure 2.
(A) A gray color region shows a serous retinal detachment in the macular area. The black arrows indicate the scanning lines of optical coherence tomography. (B) The maximal height, sectional area, tan θ were estimated in cross-sectional image by optical coherence tomography.
![jkos-49-282f2.tif](/upload/SynapseXML/0035jkos/thumb/jkos-49-282f2.gif)
Figure 3.
Scatter plot and simple linear regression line between visual acuity and sectional area of central serous chorioretinopathy (R2=0.684, P=0.001).
![jkos-49-282f3.tif](/upload/SynapseXML/0035jkos/thumb/jkos-49-282f3.gif)
Table 1.
Clinical and optical coherence tomographic characteristics of patients with central serous chorioretinopathy
Patient | Age/Sex | Side (OD/OS)* | BCVA† at first visit | Height of CSCR (µm) | Distance of CSCR (µm) | Refractive error (SE)‡(Diopter) |
---|---|---|---|---|---|---|
1 | M/39 | OD | 0.3 | 411 | 3566 | −1.00 |
2 | M/42 | OD | 0.8 | 164 | 2112 | −1.00 |
3 | M/45 | OS | 0.7 | 205 | 2600 | 1.00 |
4 | M/29 | OS | 0.3 | 412 | 3810 | −1.00 |
5 | M/52 | OS | 0.2 | 480 | 3782 | 1.00 |
6 | M/42 | OD | 0.3 | 389 | 3448 | −0.50 |
7 | M/42 | OS | 0.5 | 277 | 3121 | −1.50 |
8 | F/26 | OD | 0.4 | 475 | 3011 | −1.75 |
9 | F/54 | OS | 0.2 | 482 | 3507 | 2.75 |
10 | F/52 | OD | 0.4 | 345 | 2615 | 1.00 |
11 | M/37 | OS | 0.5 | 305 | 3250 | 1.00 |
12 | M/42 | OD | 0.5 | 352 | 3642 | −2.25 |
13 | M/42 | OD | 0.7 | 253 | 2896 | 1.25 |
14 | M/57 | OS | 0.5 | 355 | 2980 | 2.00 |
15 | M/41 | OD | 0.3 | 425 | 3555 | 1.00 |
16 | M/37 | OD | 0.6 | 370 | 3216 | −2.25 |
17 | F/39 | OD | 0.2 | 515 | 4250 | −1.50 |
18 | M/44 | OD | 0.7 | 250 | 2886 | 1.00 |
19 | F/39 | OD | 0.4 | 131 | 1121 | −1.00 |
20 | M/42 | OD | 0.8 | 66 | 542 | −2.25 |
21 | M/36 | OS | 0.6 | 365 | 3045 | −3.00 |
22 | M/42 | OD | 0.2 | 495 | 4350 | −0.50 |
23 | F/44 | OD | 0.4 | 357 | 3056 | 1.50 |
24 | F/35 | OD | 0.6 | 180 | 2300 | 1.50 |
25 | F/44 | OD | 0.6 | 257 | 2330 | 1.75 |
26 | M/48 | OD | 0.7 | 366 | 2001 | 2.00 |
27 | M/53 | OD | 0.6 | 423 | 2779 | 2.25 |
28 | M/42 | OS | 0.7 | 197 | 2102 | 0.75 |
29 | M/45 | OS | 0.3 | 425 | 3400 | 1.00 |
30 | F/53 | OS | 0.2 | 515 | 4250 | 1.50 |
Table 2.
Basic statistical analysis of serous fluid in central serous chorioretinopathy using the optical coherence tomographic image
Varible | No | Minimum | Maximum | Mean | Std. deviation |
---|---|---|---|---|---|
H (µm) | 30 | 66 | 515 | 341.40 | 120.60 |
HxD/2 (mm2) | 30 | 0.18 | 1.09 | 0.55 | 0.29 |
H/(D/2)(tan θ) | 30 | 0.16 | 0.37 | 0.22 | 0.04 |
* CSCR was defined as a serous retinal detachment that involved the center of the fovea, dye leakage from the same area by fluorescence angiography. A case of pigment epithelium detachment was excluded; H=Refer to height of serous fluid at the center of the fovea; D=sectional distance of serous fluid.