Measurement and Analysis of Serous Fluid in Central Serous Chorioretinopathy using OCT

Hyuck-Won Choi; Sang-Woong Moon; Jae-Suk Kim; Joo-Hwa Lee

doi:10.3341/jkos.2008.49.2.282

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Choi, Moon, Kim, and Lee: Measurement and Analysis of Serous Fluid in Central Serous Chorioretinopathy using OCT

Original Article

J Korean Ophthalmol Soc 2008;49(2):282-287.

Published online: 31 August 2008

DOI: https://doi.org/10.3341/jkos.2008.49.2.282

Measurement and Analysis of Serous Fluid in Central Serous Chorioretinopathy using OCT

Hyuck-Won Choi, M.D.¹, Sang-Woong Moon, M.D.², Jae-Suk Kim, M.D.¹, Joo-Hwa Lee, M.D.¹

¹Department of Ophthalmology, College of Medicine, Inje University, Sanggye Paik Hospital, Seoul, Korea

²Department of Ophthalmology, College of Medicine, Inje University, Seoul Paik Hospital, Seoul, Korea

Address reprint requests to Jae-Suk Kim, M.D., Department of Ophthalmology, Sanggye Paik Hospital #761-1 Sanggye 7-dong, Nowon-gu, Seoul 139-707, Korea Tel: 82-2-950-1096, Fax: 82-2-935-6904, E-mail: eyedoctor@freechal.com

Received 8 December 2006 Accepted 25 October 2007

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the correlation between the degree of serous fluid and best corrected visual acuity at the first visit in central serous chorioretinopathy using optical coherence tomography.

Methods

Retrospective analysis was performed for 30 eyes of 30 patients with central serous chorioretinopathy. Cross-sectional retinal images through the center of the fovea were obtained from all eyes by optical coherence tomography. The height, sectional area, and the tangent of theta (tan θ) were estimated. They were statistically analyzed and correlated with best corrected visual acuity.

Results

Mean (±SD) height of serous fluid was 341.40±120.60 µm, mean (±SD) sectional area was 0.55±0.29 mm², and mean (±SD) tan θ was 0.22±0.04. The correlation coefficients between best corrected visual acuity at the first visit and sectional area were r=-0.740 (P=0.001).

Conclusions

Optical coherence tomography is useful for the quantitative evaluation of serous neurosensory retinal detachment and estimating visual acuity in central serous chorioretinopathy.

Keywords: Central serous chorioretinopathy, Serous fluid, Optical coherence tomography

References

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Figure 1.

(A) The fundus photograph shows an grayish-white lesion to the fovea. (B) Fluorescein angiogram shows a detachment of neurosensory retina with dye leakage in the area of grayish-white lesion. (C) A tomographic sectional image of the lesion.

Figure 2.

(A) A gray color region shows a serous retinal detachment in the macular area. The black arrows indicate the scanning lines of optical coherence tomography. (B) The maximal height, sectional area, tan θ were estimated in cross-sectional image by optical coherence tomography.

Figure 3.

Scatter plot and simple linear regression line between visual acuity and sectional area of central serous chorioretinopathy (R²=0.684, P=0.001).

Table 1.

Clinical and optical coherence tomographic characteristics of patients with central serous chorioretinopathy

Patient	Age/Sex	Side (OD/OS)^*	BCVA^† at first visit	Height of CSCR (µm)	Distance of CSCR (µm)	Refractive error (SE)^‡(Diopter)
1	M/39	OD	0.3	411	3566	−1.00
2	M/42	OD	0.8	164	2112	−1.00
3	M/45	OS	0.7	205	2600	1.00
4	M/29	OS	0.3	412	3810	−1.00
5	M/52	OS	0.2	480	3782	1.00
6	M/42	OD	0.3	389	3448	−0.50
7	M/42	OS	0.5	277	3121	−1.50
8	F/26	OD	0.4	475	3011	−1.75
9	F/54	OS	0.2	482	3507	2.75
10	F/52	OD	0.4	345	2615	1.00
11	M/37	OS	0.5	305	3250	1.00
12	M/42	OD	0.5	352	3642	−2.25
13	M/42	OD	0.7	253	2896	1.25
14	M/57	OS	0.5	355	2980	2.00
15	M/41	OD	0.3	425	3555	1.00
16	M/37	OD	0.6	370	3216	−2.25
17	F/39	OD	0.2	515	4250	−1.50
18	M/44	OD	0.7	250	2886	1.00
19	F/39	OD	0.4	131	1121	−1.00
20	M/42	OD	0.8	66	542	−2.25
21	M/36	OS	0.6	365	3045	−3.00
22	M/42	OD	0.2	495	4350	−0.50
23	F/44	OD	0.4	357	3056	1.50
24	F/35	OD	0.6	180	2300	1.50
25	F/44	OD	0.6	257	2330	1.75
26	M/48	OD	0.7	366	2001	2.00
27	M/53	OD	0.6	423	2779	2.25
28	M/42	OS	0.7	197	2102	0.75
29	M/45	OS	0.3	425	3400	1.00
30	F/53	OS	0.2	515	4250	1.50

^* Oculus dexter, oculus sinster

^† best corrected visual acuity

^‡ spherical equivalent.

Table 2.

Basic statistical analysis of serous fluid in central serous chorioretinopathy using the optical coherence tomographic image

Varible	No	Minimum	Maximum	Mean	Std. deviation
H (µm)	30	66	515	341.40	120.60
HxD/2 (mm²)	30	0.18	1.09	0.55	0.29
H/(D/2)(tan θ)	30	0.16	0.37	0.22	0.04

^* CSCR was defined as a serous retinal detachment that involved the center of the fovea, dye leakage from the same area by fluorescence angiography. A case of pigment epithelium detachment was excluded; H=Refer to height of serous fluid at the center of the fovea; D=sectional distance of serous fluid.

Table 3.

Correlation coefficients for visual acuity at first visit and Variables of serous fluid in central serous chorioretinopathy

	Correlation coefficients (r)	P value
H	−0.694	0.05
HxD/2	−0.740	0.001
H/(D/2) (tanθ)	−0.295	0.113

H=refer to height of serous fluid at the center of the fovea; D=sectional distance of serous fluid.

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