Hye Jin Chung; Tae Yoon La

doi:10.3341/jkos.2008.49.10.1671

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Jin Chung and Yoon La: Solitary Kaposi’s Sarcoma of the Lower Lid in an HIV-Negative Patient

Original Article

J Korean Ophthalmol Soc 2008;49(10):1671-1675.

Published online: 7 September 2008

DOI: https://doi.org/10.3341/jkos.2008.49.10.1671

Solitary Kaposi’s Sarcoma of the Lower Lid in an HIV-Negative Patient

Hye Jin Chung, M.D, Tae Yoon La, M.D

Department of Ophthalmology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Gyeonggido, Korea

Address reprint requests to Tae Yoon La, M.D. Department of Ophthalmology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea #93 Ji-dong, Paldal-gu, Suwon-si, Gyeonggi-do 442-723, Korea Tel: 82-31-249-7340, Fax: 82-31-251-62255, E-mail: laty@catholic.ac.kr

Received 24 June 2008 Accepted 13 December 2007

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To report a case of solitary Kaposi’s sarcoma (KS) of eyelid in an HIV-negative patient, which has not yet been reported in domestics.

Case summary

A 76-year-old woman was seen at our clinic with a purplish nodular mass on her left lower lid that had grown up for 4 months prior. There were no abnormal findings in the body except eyelid. In the routine laboratory examinations, the result of HIV test was negative. The lesion was completely excised and the eyelid was reconstructed by semicircular rotational flap procedure. The histopathologic examination showed spindle cells of mild atypism, intermixed with slit-like vascular spaces and red blood cell extravastaion. These findings coincided with KS and polymerase chain reaction was positive for human herpes virus-8. During 10 months follow up, there was no evidence of tumor recurrence and systemic abnormalities.

Conclusions

We experienced that Kaposi’s sarcoma can occur solitarily in the eyelid of HIV-negative patient and favorable prognosis can be obtained by only surgical resection.

Keywords: Eyelid, HIV-negative patient, Kaposi’, s sarcoma

References

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Figure 1.

Photograph shows an indurated violaceous Broad- based mass on the left lower lid.

Figure 2.

(A) Immediate postoperative photograph after performing semicircular flap surgery to reconstruct tumor excision site of the lower lid (postoperative 1 day). (B) Photograph shows well reconstructed lower lid (posto-perative 2 months).

Figure 3.

(A) A sarcomatoid lesion is formed by spindle cells and clusters of many small capillaries (hematoxylin-eosin, ×100). (B) The vascular neoplasm is consisted of immature spindle cells with mild atypism and plump endothelial cells that line slit-like vascular channels. Extravasated red blood cells in slit-like channels and hyperchromatic nuclei in spindle cells were also observed (hematoxylin-eosin, ×400).

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