Juvenile Xanthogranuloma Presenting as a Nodule of the Eyelid

Kyoung Min Lee; Nam Ju Kim

doi:10.3341/jkos.2008.49.7.1173

Journal List > J Korean Ophthalmol Soc > v.49(7) > 1008029

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Min Lee and Kim: Juvenile Xanthogranuloma Presenting as a Nodule of the Eyelid

Original Article

J Korean Ophthalmol Soc 2008;49(7):1173-1176.

Published online: 7 September 2008

DOI: https://doi.org/10.3341/jkos.2008.49.7.1173

Juvenile Xanthogranuloma Presenting as a Nodule of the Eyelid

Kyoung Min Lee, M.D.¹, Nam Ju Kim, M.D.^1,^2,

Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea

Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggi, Korea

Address reprint requests to Nam Ju Kim, M.D. Department of Ophthalmology, Seoul National University Bundang Hospital #300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi 463-500, Korea Tel: 82-31-787-7379, Fax: 82-31-787-4057, E-mail: resourceful@hanmail.net

Received 10 April 2008 Accepted 26 November 2007

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To report one case of juvenile xanthogranuloma presenting as a unilateral nodule of the eyelid.

Case summary

A 4-year-old girl presented with a solitary eyelid nodule. There were no other ophthalmologic problems. Excisional biopsy and simple wound closure were performed. A biopsy showed intense infiltration of histiocytes, lymphocytes, and multinucleated giant cells in the dermis, which was compatible with juvenile xanthograunuloma.

Conclusion

Juvenile xanthogranuloma should be considered in the differential diagnosis of a solitary eyelid tumor.

Keywords: Eyelid tumor, Histiocytosis, Juvenile xanthogranuloma

References

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Figure 1.

Photographs of the patient’s eyelid: (A, B) Note a relatively large (7×5×4 mm) reddish yellow pedunculated solitary nodule in the canthal area.

Figure 2.

Light micrographs of excised mass. (A) hematoxylin and eosin-stained section showed intense infiltration of histiocytes, lymphocytes, and multinucleated giant cells in the dermis (H&E, ×100). (B) a multinucleated giant cell (arrow) (H&E, ×400).

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