Abstract
Purpose
This study was performed to investigate the characteristics of accommodative esotropia in patients who successfully discontinued their use of glasses and to determine which factors are predictive of successfully discontinuing the use of glasses.
Methods
A retrospective review was performed of 40 patients with accommodative esotropia who were orthophoric without glasses (group A) and 58 patients with persistent esotropia without glasses (group B). The exclusion criteria were as follows: a follow-up of less than 5 years, age younger than 10 years old, less than 1.50 diopters of hyperopia, or previous strabismus surgery. We analyzed the relationships between the factors and the resolution of esotropia.
Results
The mean distance esotropia (30.1 vs 24.3 prism diopters), the degree of hyperopia (+5.3 vs +3.9 diopters) and the interval between the initial prescription of glasses and the initiation of discontinuing their use were predictors of successful discontinuation of glasses in group A and B (p<.05).
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References
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Table 1.
Demographics and initial clinical characteristics of patients in two groups
Glasses discontinued group (n=40) | Glasses still worn group (n=58) | P-value | |
---|---|---|---|
Sex, n (%) | 0.056* | ||
Male | 23 (57.5) | 22 (37.9) | |
Female | 17 (42.5) | 36 (62.1) | |
Family History of strabismus, n (%) | 2 (5.0) | 7 (12.1) | 0.302† |
Amblyopia, n (%) | 13 (32.5) | 16 (27.6) | 0.600* |
High AC/A ratio, n (%) | 2 (5.0) | 1 (1.7) | 0.565† |
Age esotropia developed, mo (SD) | 24.7 (16.8) | 23.0 (15.7) | 0.624‡ |
Age esotropia diagnosed, mo (SD) | 44.1 (16.6) | 39.8 (17.3) | 0.229‡ |
Age glasses prescribed, mo (SD) | 44.3 (16.6) | 40.3 (16.7) | 0.251‡ |
Age at last follow-up, yr (SD) | 15.7 (2.6) | 15.6 (3.0) | 0.957‡ |
Best corrected visual acuity (dominant eye), LogMAR (SD) | 0.49 (0.2) | 0.52 (0.2) | 0.413‡ |
Best corrected visual acuity (non-dominant eye), LogMAR (SD) | 0.66 (0.2) | 0.67 (0.3) | 0.735‡ |
Distant esotropia, PD (SD) | 24.3 (10.6) | 30.1 (10.9) | 0.010‡ |
Near esotroipa, PD (SD) | 25.7 (10.6) | 30.2 (10.9) | 0.046‡ |
Spherical equivalent (higher eye), D (SD) | 4.3 (1.8) | 5.9 (2.1) | 0.000‡ |
Spherical equivalent (lower eye), D (SD) | 3.9 (1.8) | 5.3 (2.1) | 0.001‡ |
Follow-up interval, mo (SD) | 144.0 (38.0) | 147.4 (39.5) | 0.663‡ |
Total follow-up interval, mo (SD) | 146.0 (38.4) |
Table 2.
Clinical characteristics in two groups at final examination
Glasses discontinued group (n=40) | Glassesstill worn group (n=58) | P-value | |
---|---|---|---|
Time between esotropia developed and glasses prescribed, mo (SD) | 19.7 (14.8) | 17.3 (14.1) | 0.434* |
Time between esotropia diagnosed and glasses prescribed, mo (SD) | 0.2 (0.8) | 0.5 (2.7) | 0.527* |
Age weaning started, mo (SD) | 84.8 (17.9) | 87.7 (18.3) | 0.430* |
Time between glasses prescribed and weaning started, mo (SD) | 40.5 (20.0) | 47.4 (19.1) | 0.087* |
Amblyopia, n (%) | 5 (12.5) | 11 (19.0) | 0.395† |
Best corrected visual acuity (dominant eye), LogMAR (SD) | 0.01 (0.05) | 0.01 (0.06) | 0.969* |
Best corrected visual acuity (non-dominant eye), LogMAR (SD) | 0.06 (0.17) | 0.05 (0.14) | 0.965* |
Distant esotropia, PD (SD) | 1.8 (2.7) | 2.7 (3.0) | 0.115* |
Near esotroipa, PD (SD) | 2.7 (3.1) | 3.0 (3.0) | 0.657* |
Spherical equivalent (higher eye), D (SD) | 0.9 (1.5) | 3.6 (1.8) | 0.000* |
Spherical equivalent (lower eye), D (SD) | 0.4 (1.5) | 2.9 (1.9) | 0.000* |
Decrease of spherical equivalent (higher eye), D (SD) | 3.5 (1.6) | 2.3 (1.5) | 0.000* |
Decrease of spherical equivalent (lower eye), D (SD) Age glasses discontinued, yr (SD) | 3.6 (1.6) 14.4 (2.4) | 2.4 (1.7) | 0.001* |
Table 3.
Sensory tests in two groups during follow-up
Glasses discontinued group | Glasses still worn group | P-value | |
---|---|---|---|
Lang stereotest passed, % (n) | 15.0 (6/40) | 31.9 (15/47) | 0.066* |
Titmus stereotest, sec/arc (SD, n) | 542.7 (532.5, 33) | 373.0 (509.1, 40) | 0.169† |
Worth 4-dot test | |||
Fusion at distance and near, % (n) | 52.9 (18/34) | 44.4 (16/36) | 0.477* |
Fusion at distance, % (n) | 52.9 (18/34) | 44.4 (16/36) | 0.477* |
Fusion at near, % (n) | 88.2 (30/34) | 83.3 (30/36) | 0.736* |
Table 4.
Predictive factors of successful weaning from glasses
Predictive factors | Relative risk (95% CI) | P-value* |
---|---|---|
Age esotropia diagnosed (< 4 yr) | 0.605 (0.258 to 1.419) | 0.248 |
Age glasses prescribed (< 4 yr) | 0.605 (0.258 to 1.419) | 0.248 |
Distant esotropia (< 20PD) | 3.046 (1.096 to 8.462) | 0.033 |
Near esotropia (< 20PD) | 0.848 (0.255 to 2.823) | 0.789 |
Spherical equivalent (lower eye, < 3D) | 5.158 (2.017 to 13.190) | 0.001 |
Age weaning started (< 8 yr) | 1.517 (0.586 to 3.925) | 0.391 |
Time between esotropia developed and glasses prescribed (≤ 2 yr) | 0.900 (0.399 to 2.032) | 0.799 |
Time between glasses prescribed and weaning started (< 3 yr) | 5.158 (2.076 to 12.949) | 0.000 |