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Journal List > J Korean Ophthalmol Soc > v.48(12) > 1007992

Lee and Kim: Clinical Characteristics of Accommodative Esotropia with Successful Wearing out of Glasses

Abstract

Purpose

This study was performed to investigate the characteristics of accommodative esotropia in patients who successfully discontinued their use of glasses and to determine which factors are predictive of successfully discontinuing the use of glasses.

Methods

A retrospective review was performed of 40 patients with accommodative esotropia who were orthophoric without glasses (group A) and 58 patients with persistent esotropia without glasses (group B). The exclusion criteria were as follows: a follow-up of less than 5 years, age younger than 10 years old, less than 1.50 diopters of hyperopia, or previous strabismus surgery. We analyzed the relationships between the factors and the resolution of esotropia.

Results

The mean distance esotropia (30.1 vs 24.3 prism diopters), the degree of hyperopia (+5.3 vs +3.9 diopters) and the interval between the initial prescription of glasses and the initiation of discontinuing their use were predictors of successful discontinuation of glasses in group A and B (p<.05).

Conclusions

Some patients with accommodative esotropia may be successfully weared out of glasses. A smaller esotropic angle, lesser degree of hyperopia, and earlier initiation of wearing appear to be favorable factors.

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References

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Table 1.
Demographics and initial clinical characteristics of patients in two groups
  Glasses discontinued group (n=40) Glasses still worn group (n=58) P-value
Sex, n (%) 0.056*
 Male 23 (57.5) 22 (37.9)
 Female 17 (42.5) 36 (62.1)
Family History of strabismus, n (%) 2 (5.0) 7 (12.1) 0.302
Amblyopia, n (%) 13 (32.5) 16 (27.6) 0.600*
High AC/A ratio, n (%) 2 (5.0) 1 (1.7) 0.565
Age esotropia developed, mo (SD) 24.7 (16.8) 23.0 (15.7) 0.624
Age esotropia diagnosed, mo (SD) 44.1 (16.6) 39.8 (17.3) 0.229
Age glasses prescribed, mo (SD) 44.3 (16.6) 40.3 (16.7) 0.251
Age at last follow-up, yr (SD) 15.7 (2.6) 15.6 (3.0) 0.957
Best corrected visual acuity (dominant eye), LogMAR (SD) 0.49 (0.2) 0.52 (0.2) 0.413
Best corrected visual acuity (non-dominant eye), LogMAR (SD) 0.66 (0.2) 0.67 (0.3) 0.735
Distant esotropia, PD (SD) 24.3 (10.6) 30.1 (10.9) 0.010
Near esotroipa, PD (SD) 25.7 (10.6) 30.2 (10.9) 0.046
Spherical equivalent (higher eye), D (SD) 4.3 (1.8) 5.9 (2.1) 0.000
Spherical equivalent (lower eye), D (SD) 3.9 (1.8) 5.3 (2.1) 0.001
Follow-up interval, mo (SD) 144.0 (38.0) 147.4 (39.5) 0.663
Total follow-up interval, mo (SD) 146.0 (38.4)

PD = prism diopters; D = diopters.

* Chi-square test;

Fisher's exact test;

Student t-test.

Table 2.
Clinical characteristics in two groups at final examination
  Glasses discontinued group (n=40) Glassesstill worn group (n=58) P-value
Time between esotropia developed and glasses prescribed, mo (SD) 19.7 (14.8) 17.3 (14.1) 0.434*
Time between esotropia diagnosed and glasses prescribed, mo (SD) 0.2 (0.8) 0.5 (2.7) 0.527*
Age weaning started, mo (SD) 84.8 (17.9) 87.7 (18.3) 0.430*
Time between glasses prescribed and weaning started, mo (SD) 40.5 (20.0) 47.4 (19.1) 0.087*
Amblyopia, n (%) 5 (12.5) 11 (19.0) 0.395
Best corrected visual acuity (dominant eye), LogMAR (SD) 0.01 (0.05) 0.01 (0.06) 0.969*
Best corrected visual acuity (non-dominant eye), LogMAR (SD) 0.06 (0.17) 0.05 (0.14) 0.965*
Distant esotropia, PD (SD) 1.8 (2.7) 2.7 (3.0) 0.115*
Near esotroipa, PD (SD) 2.7 (3.1) 3.0 (3.0) 0.657*
Spherical equivalent (higher eye), D (SD) 0.9 (1.5) 3.6 (1.8) 0.000*
Spherical equivalent (lower eye), D (SD) 0.4 (1.5) 2.9 (1.9) 0.000*
Decrease of spherical equivalent (higher eye), D (SD) 3.5 (1.6) 2.3 (1.5) 0.000*
Decrease of spherical equivalent (lower eye), D (SD) Age glasses discontinued, yr (SD) 3.6 (1.6) 14.4 (2.4) 2.4 (1.7) 0.001*

PD = prism diopters; D = diopters.

* Student t-test;

Chi-square test.

Table 3.
Sensory tests in two groups during follow-up
  Glasses discontinued group Glasses still worn group P-value
Lang stereotest passed, % (n) 15.0 (6/40) 31.9 (15/47) 0.066*
Titmus stereotest, sec/arc (SD, n) 542.7 (532.5, 33) 373.0 (509.1, 40) 0.169
Worth 4-dot test
 Fusion at distance and near, % (n) 52.9 (18/34) 44.4 (16/36) 0.477*
 Fusion at distance, % (n) 52.9 (18/34) 44.4 (16/36) 0.477*
 Fusion at near, % (n) 88.2 (30/34) 83.3 (30/36) 0.736*

sec/arc = seconds/arc.

* Chi-square test;

Student t-test.

Table 4.
Predictive factors of successful weaning from glasses
Predictive factors Relative risk (95% CI) P-value*
Age esotropia diagnosed (< 4 yr) 0.605 (0.258 to 1.419) 0.248
Age glasses prescribed (< 4 yr) 0.605 (0.258 to 1.419) 0.248
Distant esotropia (< 20PD) 3.046 (1.096 to 8.462) 0.033
Near esotropia (< 20PD) 0.848 (0.255 to 2.823) 0.789
Spherical equivalent (lower eye, < 3D) 5.158 (2.017 to 13.190) 0.001
Age weaning started (< 8 yr) 1.517 (0.586 to 3.925) 0.391
Time between esotropia developed and glasses prescribed (≤ 2 yr) 0.900 (0.399 to 2.032) 0.799
Time between glasses prescribed and weaning started (< 3 yr) 5.158 (2.076 to 12.949) 0.000

CI = confidence interval; PD = prism diopters; D = diopters.

* Cox proportional hazard regression analysis.

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