Cosmetic Repair of Band Keratopathy Using Stained Amniotic Membrane

Cinoo Kim; Young Keun Han; Joon Young Hyon; Won Ryang Wee; Jin Hak Lee; Ji Won Kwon

doi:10.3341/jkos.2007.48.11.1459

Journal List > J Korean Ophthalmol Soc > v.48(11) > 1007956

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Kim, Han, Hyon, Wee, Lee, and Kwon: Cosmetic Repair of Band Keratopathy Using Stained Amniotic Membrane

Original Article

J Korean Ophthalmol Soc 2007;48(11):1459-1465.

Published online: 28 August 2007

DOI: https://doi.org/10.3341/jkos.2007.48.11.1459

Cosmetic Repair of Band Keratopathy Using Stained Amniotic Membrane

Cinoo Kim, M.D.¹, Young Keun Han, M.D.^1,², Joon Young Hyon, M.D.^1,³, Won Ryang Wee, M.D.¹, Jin Hak Lee, M.D.^1,³, Ji Won Kwon, M.D.^1,⁴

¹Department of Ophthalmology, Seoul National University College of Medicine, Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea

²Department of Ophthalmology, Seoul National University Boramae Hospital, Seoul, Korea

³Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggi, Korea

⁴Seoul National University Hospital Healthcare System Gangnam Center, Healthcare Institute, Seoul, Korea

Address reprint requests to Ji Won Kwon, M.D., Department of Ophthalmology, Seoul National University College of Medicine, #28 Yongon-dong, Chongno-gu, Seoul 110-744, Korea, Tel: 82-2-2072-2438, Fax: 82-2-741-3187, E-mail: eyeminerva@yahoo.co.kr

Received 21 November 2006 Accepted 7 19 2007

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the efficacy of stained amniotic membrane transplantation (AMT) for cosmetic repair of band keratopathy.

Methods

Eight eyes from 8 patients with band keratopathy without the possibility of visual improvement were treated with corneal tattooing and stained AMT. Calcific plaques were removed with EDTA and a blade prior to the tattooing. Tattooing by the injection of tissue marking dye into the corneal stroma was performed in corneal opacities. The remaining opacity, which could not be treated with corneal tattooing, was treated with black dye-stained AMT.

Results

The most common cause of band keratopathy was trauma (50%) and the mean time to epithelial healing was 11.3 days. All patients showed satisfactory results with cosmetic staining. Recurring cases and significant complications were not observed during the mean follow-up period of 7.4 months.

Conclusions

Cosmetic repair by corneal tattooing and stained AMT is an effective treatment for band keratopathy and is not associated with any significant complications.

Keywords: Band keratopathy, Corneal opacity, Corneal tattooing, Stained amniotic membrane

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Figure 1.

A 20-year-old female patient with band keratopathy in the left eye. (A) and (C): Before tattooing and stained amniotic membrane transplantation (AMT). (B) and (D): After tattooing and stained AMT.

Figure 2.

A 63-year-old female patient with band keratopathy in the right eye. (A) and (C): Before tattooing and stained AMT. (B) and (D): After tattooing and stained AMT.

Table 1.

Characteristics of patients

Case	Age (Yr)	Sex	F/U (Month)	Visual acuity	Cause of band keratopathy	Comorbidity	Postoperativecomplications
1	19	M	13	NLP^*	PHPV^‡		Injection, FBS^#
2	36	M	8	LP^†	Trauma		FBS
3	20	F	10	NLP	Infection		FBS
4	63	F	6	LP	Trauma		Injection
5	13	M	8	NLP	Cataract surgery
6	14	F	7	NLP	PHPV, glaucoma	Sensory ET^§	Injection
7	25	M	4	NLP	Trauma	Cataract, sensory XT^Π	FBS
8	18	M	3	NLP	Trauma	Sensory XT

^* NLP: no light perception

^† LP : light perception

^‡ PHPV: persistent hyperplastic primary vitreous

^§ ET: esotropia

^Π XT: exotropia

^# FBS: foreign body sensation

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