Abstract
Purpose
To report a case of macular edema after the use of the oral hypoglycemic agent rosiglitazone.
Methods
A 43-year-old man, who had diabetic mellitus and was on oral rosiglitazone therapy, complained of a visual disturbance in his left eye. After fundus examination and optical coherence tomography, macular edema was observed, therefore rosiglitazone therapy was discontinued.
References
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Figure 1.
Optical coherence tomography (OCT) finding of the patient's left eye, 1 month after the development of visual disturbance showed cyst-like accumulation of subretinal fluid at the central macula.
![jkos-48-1425f1.tif](/upload/SynapseXML/0035jkos/thumb/jkos-48-1425f1.gif)
Figure 2.
Optical coherence tomography (OCT) of the patient's left eye, two weeks after discontinuation of rosiglitazone showed marked decrease of subretinal fluid at the central macula.
![jkos-48-1425f2.tif](/upload/SynapseXML/0035jkos/thumb/jkos-48-1425f2.gif)
Figure 3.
(A) Fundus photo of the patient‘s left eye, two weeks after discontinuation of rosiglitazone showed multiple dot and blot shaped retinal hemorrhages and circinate hard exudates around macula. (B) Late phase fluorescein angiogram showed diffuse fluorescein leaking from new vessel elsewhere and fluorescein pooling at remnant macular edema.
![jkos-48-1425f3.tif](/upload/SynapseXML/0035jkos/thumb/jkos-48-1425f3.gif)