Abstract
Many disorders can cause either acute or chronic vomiting. However, in most cases, vomiting is self-limited. A correct diagnosis is possible by conducting careful histories and physical examinations. In cases of severe vomiting, further testing, including laboratory studies, radiological images, endoscopic evaluation, and gastrointestinal motility tests, can also be considered. The correction of clinical consequences of vomiting should be initiated, including dehydration, electrolyte imbalances, malnutrition, and suppression of symptoms via the use empirical antiemetic treatments. Moreover, underlying disorders should be treated using dietary, pharmacological, and even surgical interventions.
References
1. Quigley EM, Hasler WL, Parkman HP. AGA technical review on nausea and vomiting. Gastroenterology. 2001; 120:263–286.
2. Miller AD. Central mechanisms of vomiting. Dig Dis Sci. 1999; 44:8 Suppl. 39S–43S.
3. Koch KL. Unexplained nausea and vomiting. Curr Treat Options Gastroenterol. 2000; 3:303–314.
4. Fraga XF, Malagelada JR. Nausea and vomiting. Curr Treat Options Gastroenterol. 2002; 5:241–250.
5. DiBaise JK, Brand RE, Lyden E, Tarantolo SR, Quigley EM. Gastric myoelectrical activity and its relationship to the development of nausea and vomiting after intensive chemotherapy and autologous stem cell transplantation. Am J Gastroenterol. 2001; 96:2873–2881.
6. Malagelada JR, Camilleri M. Unexplained vomiting: a diagnostic challenge. Ann Intern Med. 1984; 101:211–218.
7. Stanghellini V, Talley NJ, Chan F, et al. Rome IV - Gastroduodenal disorders. Gastroenterology. pii: S0016-5085(16)00177-3. 2016 Feb 15. [Epub ahead of print].
8. Abell TL, Adams KA, Boles RG, et al. Cyclic vomiting syndrome in adults. Neurogastroenterol Motil. 2008; 20:269–284.
9. Absah I, Rishi A, Talley NJ, Katzka D, Halland M. Rumination syndrome: pathophysiology, diagnosis, and treatment. Neurogastroenterol Motil. 2017; 29.
10. Parkman HP, Camilleri M, Farrugia G, et al. Gastroparesis and functional dyspepsia: excerpts from the AGA/ANMS meeting. Neurogastroenterol Motil. 2010; 22:113–133.
11. Tack J, Carbone F, Rotondo A. Gastroparesis. Curr Opin Gastroenterol. 2015; 31:499–505.
12. Tack J. The difficult patient with gastroparesis. Best Pract Res Clin Gastroenterol. 2007; 21:379–391.
13. Stanghellini V, Camilleri M, Malagelada JR. Chronic idiopathic intestinal pseudo-obstruction: clinical and intestinal manometric findings. Gut. 1987; 28:5–12.
14. Tack J, Carbone F. Functional dyspepsia and gastroparesis. Curr Opin Gastroenterol. 2017; 33:446–454.
15. Pandolfino JE, Gawron AJ. Achalasia: a systematic review. JAMA. 2015; 313:1841–1852.
16. Li AC, Jourdan M, Thompson RP. The superior mesenteric artery syndrome; an unusual cause of vomiting. Hepatogastroenterology. 2005; 52:469–470.
17. Hokama A, Tomiyama R, Kishimoto K, Kinjo F, Saito A, Matayoshi M. Chronic intermittent vomiting after scoliosis surgery. Gut. 2005; 54:222. 281.
18. Tiwari AK, Bierhals A, Wang JS. An uncommon cause of post-prandial nausea and vomiting. Superior mesenteric artery syndrome. Gastroenterology. 2013; 145:520. 698.
19. Acosta A, Camilleri M. Prokinetics in gastroparesis. Gastroenterol Clin North Am. 2015; 44:97–111.
20. Masaoka T, Tack J. Gastroparesis: current concepts and management. Gut Liver. 2009; 3:166–173.
21. Leelakanok N, Holcombe A, Schweizer ML. Domperidone and risk of ventricular arrhythmia and cardiac death: a systematic review and meta-analysis. Clin Drug Investig. 2016; 36:97–107.
22. Simmons K, Parkman HP. Granisetron transdermal system improves refractory nausea and vomiting in gastroparesis. Dig Dis Sci. 2014; 59:1231–1234.
23. Brygger L, Herrstedt J;. AgeCare). 5-Hydroxytryptamine3 receptor antagonists and cardiac side effects. Expert Opin Drug Saf. 2014; 13:1407–1422.
24. Aapro M, Carides A, Rapoport BL, Schmoll HJ, Zhang L, Warr D. Aprepitant and fosaprepitant: a 10-year review of efficacy and safety. Oncologist. 2015; 20:450–458.
25. Karamanolis G, Tack J. Promotility medications--now and in the future. Dig Dis. 2006; 24:297–307.
26. Tack J, Vanormelingen C. Management of gastroparesis: beyond basics. Curr Treat Options Gastroenterol. 2014; 12:468–477.