A Review of Diagnosis of GERD

In Du Jeong

doi:10.4166/kjg.2017.69.2.96

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Jeong: A Review of Diagnosis of GERD

Review Article

Korean J Gastroenterol 2017;69(2):96-101.

Published online: 4 October 2017

DOI: https://doi.org/10.4166/kjg.2017.69.2.96

A Review of Diagnosis of GERD

In Du Jeong

Division of Gastroenterology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea

Correspondence to: In Du Jeong, Division of Gastroenterology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, 877 Bangeojinsunhwando-ro, Dong-gu, Ulsan 44033, Korea. Tel: +82-52-250-7029, Fax: +82-52-250-7048, E-mail: jidmd@uuh.ulsan.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The prevalence of gastroesophageal reflux disease (GERD) and the incidence of some of its complications have risen strikingly over the last few decades. With the accumulation in our understanding on the pathophysiology of GERD along with the development of proton pump inhibitors, the diagnostic and therapeutic approaches to the GERD have changed dramatically over the past decade. However, The GERD still poses a problem to many clinicians since the spectrum of the disease has evolved to encompass more challenging presentations such as refractory GERD and extraesophageal manifestations. The aim of this article was to provide a review of available current diagnostic tests of the GERD, includes proton pump inhibitor test, ambulatory pH monitoring, impedance pH monitoring, mucosa impedance, and high resolution manometry. This review discusses different modalities for the work up of GERD.

Keywords: Gastroesophageal reflux disease, Proton pump inhibitor test, Esophageal pH monitoring, Impedance pH monitoring, Mucosa impedance

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