Journal List > Korean J Gastroenterol > v.68(2) > 1007607

Kim, Hwang, Lee, and Hwang: Rare Case of Primary Gastric Burkitt Lymphoma in a Child

Abstract

Primary gastric tumors are very rare in children. Burkitt lymphoma is a common type of non-Hodgkin's lymphoma, and gastric Burkitt lymphoma usually occurs in the aged. When involving the gastrointestinal tract, primary gastric Burkitt lymphoma is very rare in younger childhood. Many gastric lymphomas including mucosa-associated lymphoid tissue lymphoma are associated with Helicobacter pylori infection or acute bleeding symptom. We report a seven-year-old boy who presented with only some vomiting and postprandial pain. His upper gastrointestinal endoscopy and biopsy revealed a large primary Burkitt lymphoma with no acute bleeding and no evidence of H. pylori infection. After chemotherapy, he remains in remission.

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Fig. 1.
Simple abdominal X-ray shows mass-like lesion in the epigastric and in the left infra-phrenic area.
kjg-68-87f1.tif
Fig. 2.
Contrast-enhanced coronal CT reveals diffuse thickening of the gastric wall with heterogeneous enhancement.
kjg-68-87f2.tif
Fig. 3.
Gastroscopic finding. A huge well-demarcated ulcerative lesion with neighboring mucosal elevation and irregular margin is seen at the cardia.
kjg-68-87f3.tif
Fig. 4.
Gastric tissue histology. (A) This slide shows lymphoid and monomorphic round cells is diffusely infiltrated within mucosa (H&E, ×400). The immunohistochemistry slides show the destructive infiltration of B-cell lineage. The tumor cells are positive for (B) CD20 (×400), (C) CD10 (×400), and (D) Bcl-6 protein (×400). (E) Total tumor cells are Ki-67 positive (×400).
kjg-68-87f4.tif
Fig. 5.
Fludeoxyglucose (FDG) PET/CT. Diffuse and nodular FDG uptake in the stomach, omentum, mesentery, and pelvic dependent peritoneum.
kjg-68-87f5.tif
Fig. 6.
Gastroscopic finding after three years. Normal appearance of gastric mucosa is seen at the same location (the previous lesion of cardia).
kjg-68-87f6.tif
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