Abstract
Most esophageal lipomas are discovered incidentally and are small and asymptomatic. However, large (>4 cm) lipomas may cause various symptoms, including dysphagia, regurgitation, or epigastric discomfort. We present a 45-year-old woman with intermittent sudden choking and globus pharyngeus. Upper gastrointestinal endoscopy and endoscopic ultrasound revealed an approximately 10.0×1.5 cm pedunculated subepithelial tumor in the upper esophagus, identified as the cause of her symptoms. A thoracic computed tomography scan revealed a fat attenuated longitudinal mass along the upper esophagus, suggestive of a lipoma. Endoscopic resection of the lesion was performed with a detachable snare to relieve her symptoms, and the pathologic findings were consistent with a lipoma.
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Fig. 1.
(A) Endoscopic images showing a pedunculated subepithelial tumor with a large pedicle covered with normal mucosa originating in the cervical esophagus (arrow). (B) Positive “pillow sign” and the yellowish, smooth mucosal surface are visible.

Fig. 2.
(A) Thoracic computed tomography scan showing a longitudinal mass with fat density (arrow), elongated approximately 8 cm along the upper esophagus. (B) Endoscopic ultrasound showing a hyperechoic lesion with a smooth margin arising from the submucosal layer of the esophagus (arrowheads).
