A Case of Gastric Lymphoepithelioma-like Carcinoma Presenting as a Subepithelial Tumor Diagnosed by Endoscopic Resection

Sun Hyoung Hong; In Du Jeong

doi:10.4166/kjg.2014.64.4.246

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Hong and Jeong: A Case of Gastric Lymphoepithelioma-like Carcinoma Presenting as a Subepithelial Tumor Diagnosed by Endoscopic Resection

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Korean J Gastroenterol 2014;64(4):246-249.

Published online: 4 October 2014

DOI: https://doi.org/10.4166/kjg.2014.64.4.246

A Case of Gastric Lymphoepithelioma-like Carcinoma Presenting as a Subepithelial Tumor Diagnosed by Endoscopic Resection

Sun Hyoung Hong, In Du Jeong

Division of Gastroenterology, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea

Correspondence to: In Du Jeong, Division of Gastroenterology, Department of Internal Meicine, Ulsan University Hospital, 877 Bangeojinsunhwan-doro, Dong-gu, Ulsan 682-714, Korea. Tel: +82-52-250-7029, Fax: +82-52-250-7048, E-mail: jidmd@uuh.ulsan.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

References

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Fig. 1.

Endoscopic finding. About 2.0 cm sized protruding lesion with surface erosion and bridging folds is seen on the less curvature of low body.

Fig. 2.

EUS finding. EUS shows 2.0 cm sized hypoecohoic mass involving mainly the third layer and focal fourth layer of gastric wall.

Fig. 3.

Endoscopic findings during endoscopic resection. (A) Whitish mass lesion is revealed after mucosa denudation. (B) The mass lesion is shown to have invaded the proper muscle layer.

Fig. 4.

Histologic findings (H&E). (A) The submucosal tumor is well demarcated (×40). (B) Large sized atypical cells are seen with many lymphocytes on the background (×400).

Fig. 5.

Immunohistochemical staining. Large sized atypical tumor cells show positive reaction for cytokeratin stain (×400).

Fig. 6.

In situ hybridization for Epstein-Barr virus (EBV)-encoded RNAs. Large sized atypical tumor cells show positive reaction with strong nuclear staining while the surrounding lymphoid cells show no reaction (×200).

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