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Kim: Standard Value of Serum Alanine Aminotransferase: Is It Fixed or Varied?

Editorial

Korean J Gastroenterol 2014;64(4):179-181.

Published online: 4 October 2014

DOI: https://doi.org/10.4166/kjg.2014.64.4.179

Standard Value of Serum Alanine Aminotransferase: Is It Fixed or Varied?

Sang Gyune Kim

Department of Internal Medicine, Digestive Disease Center and Research Institute, Soonchunhyang University Hospital Bucheon, Bucheon, Korea

Correspondence to: Sang Gyune Kim, Department of Internal Medicine, Soonchunhyang University Hospital Bucheon, 170 Jomaru-ro, Wonmi-gu, Bucheon 420-767, Korea. Tel: +82-32-621-5079, Fax: +82-32-621-6927, E-mail: mcnulty@schmc.ac.kr

Copyright © 2014 Korean Ophthalmological Society

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Article

Detailed Distribution of Liver Enzymes according to Gender, Age, and Body Mass Index in Health Checkup Subjects

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References

1. Kim WR, Flamm SL, Di Bisceglie AM, Bodenheimer HC. Public Policy Committee of the American Association for the Study of Liver Disease. Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease. Hepatology. 2008; 47:1363–1370.

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10. Piton A, Poynard T, Imbert-Bismut F, et al. Factors associated with serum alanine transaminase activity in healthy subjects: consequences for the definition of normal values, for selection of blood donors, and for patients with chronic hepatitis C. MULTIVIRC Group. Hepatology. 1998; 27:1213–1219.

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12. Choi SH, Yang JI, Lee C, et al. Detailed distribution of liver enzymes according to gender, age, and body mass index in health checkup subjects. Korean J Gastroenterol. 2014; 64:213–223.

13. Lee JK, Shim JH, Lee HC, et al. Estimation of the healthy upper limits for serum alanine aminotransferase in Asian populations with normal liver histology. Hepatology. 2010; 51:1577–1583.

14. Dufour DR. Alanine aminotransferase: is it healthy to be “normal”? Hepatology. 2009; 50:1699–1701.

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Table 1.

Ninety-five Percentile of Upper Level of ALT and AST Value according to BMI

	BMI (kg/m²)
	≤23.5			≤25			≤30
	Total	Male	Female	Total	Male	Female	Total	Male	Female
ALT (IU/L)	42	50	34	46	55	36	56	66	39
AST (IU/L)	35	38	32	36	39	33	40	43	34

Data from the article of Choi, et al. (Korean J Gastroenterol 2014;64:213-223).¹²

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