Current Issues on Gastroesophageal Reflux Disease

Jie-Hyun Kim; Beom Jin Kim; Sang Wook Kim; Sung Eun Kim; Yeon Soo Kim; Hye Young Sung; Tae-Hoon Oh; In Du Jeong; Moo In Park

doi:10.4166/kjg.2014.64.3.127

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Kim, Kim, Kim, Kim, Kim, Sung, Oh, Jeong, Park, and The Korean Society of Neurogastroenterology and Motility GERD and Esophageal Function Research Committee: Current Issues on Gastroesophageal Reflux Disease

Review Article

Korean J Gastroenterol 2014;64(3):127-132.

Published online: 4 October 2014

DOI: https://doi.org/10.4166/kjg.2014.64.3.127

Current Issues on Gastroesophageal Reflux Disease

Jie-Hyun Kim, Beom Jin Kim¹, Sang Wook Kim², Sung Eun Kim³, Yeon Soo Kim⁴, Hye Young Sung⁵, Tae-Hoon Oh⁶, In Du Jeong⁷, Moo In Park³; The Korean Society of Neurogastroenterology and Motility GERD and Esophageal Function Research Committee

Departments of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea

¹Chung-Ang University College of Medicine, Seoul, Korea

²Chonbuk National University Medical School, Jeonju, Korea

³Kosin University College of Medicine, Busan, Korea

⁴Hallym University College of Medicine, Chuncheon, Korea

⁵Wonkwang University College of Medicine, Iksan, Korea

⁶Inje University College of Medicine, Seoul, Korea

⁷University of Ulsan College of Medicine, Ulsan, Korea

Correspondence to: Moo In Park, Department of Internal Medicine, Kosin University College of Medicine, 262 Gamcheon-ro, Seo-gu, Busan 602-702, Korea. Tel: +82-51-990-5061, Fax: +82-51-990-3005, E-mail: mipark@kosinmed.or.kr

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Gastroesophageal reflux disease (GERD) is one of the most common problems in gastrointestinal disorders. With the increase in our understanding on the pathophysiology of GERD along with the development of proton pump inhibitors, the diagnostic and therapeutic approaches to GERD have changed dramatically over the past decade. However, GERD still poses a problem to many clinicians since the spectrum of the disease has evolved to encompass more challenging presentations such as refractory GERD and extraesophageal manifestations. This has led to significant confusion regarding the optimal approach to these patients. This article aims to discuss current issues on GERD.

Keywords: Gastroesophageal reflux, Pathophysiology, Diagnosis, Therapeutics

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