A Case of Celiac Disease

Tae-Geun Gweon; Chul-Hyun Lim; Seoug-Wook Byeon; Myong-Ki Baeg; Jong-Yul Lee; Sung-Jin Moon; Jin-Su Kim; Myung-Gyu Choi

doi:10.4166/kjg.2013.61.6.338

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Gweon, Lim, Byeon, Baeg, Lee, Moon, Kim, and Choi: A Case of Celiac Disease

Case Report

Korean J Gastroenterol 2013;61(6):338-342.

Published online: 4 October 2013

DOI: https://doi.org/10.4166/kjg.2013.61.6.338

A Case of Celiac Disease

Tae-Geun Gweon, Chul-Hyun Lim, Seoug-Wook Byeon, Myong-Ki Baeg, Jong-Yul Lee, Sung-Jin Moon, Jin-Su Kim, Myung-Gyu Choi

Department of Internal Medicine, The Catholic University College of Medicine, Seoul, Korea

Correspondence to: Chul-Hyun Lim, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Banpo-daero 222, Seocho-gu, Seoul 137-701, Korea. Tel: +82-2-2258-2083, Fax: +82-2-2258-2055, E-mail: diluck@catholic.ac.kr

Received 25 September 201216 October 2012 Accepted 24 October 2012

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Celiac disease is a chronic absorptive disorder of the small intestine caused by gluten. The prevalence rate of celiac disease is 1% in Western countries. But, it is rare in Asian countries, and there is no celiac disease reported in Korea. Here, we report a case of celiac disease. An 36-years-old woman complained nonspecific abdominal pain and diarrhea. She had anemia and was taking medication for osteoporosis. Colonoscopy showed no abnormality except shallow ulcer at the terminal ileum. Gastroduodenoscopy showed micronodularity at the duodenum 2nd and 3rd portion. Capsule endoscopy and enteroscopy showed villous atrophy and blunting of villi from the duodenum. Small intestinal pathology showed villous atrophy with lymphocyte infiltration. After gluten free diet, diarrhea, abdominal pain, anemia and osteoporosis were improved. And, she felt well-being sensation. This is a first case of celiac disease in Korea.

Keywords: Celiac disease, Gluten free diet

References

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Fig. 1.

Colonoscopic finding. Colonoscopy showed shallow ulceration at the terminal ileum.

Fig. 2.

Abdominal CT finding. Abdominal CT showed multiple conglomerated lymphadenopathies in the mesentery.

Fig. 3.

Endoscopic finding. It showed diffuse micronodularity at the duodenal 2nd portion.

Fig. 4.

Microscopic findings of the duodenal 2nd portion. (A) Villous atrophy, crypt hyperplasia in a biopsy of duodenum 2nd portion (H&E, ×100).(B) Increase in the intraepithelial lymphocytes was noted (H&E, ×400).

Fig. 5.

Capsule endoscopic finding. It showed blunted villi with focal atrophic change at the jejunum.

Fig. 6.

Enteroscopic finding. It showed diffuse atrophic villous mucosal change with blunting of villi at the jejunum.

Fig. 7.

Microscopic findings of the jejunum. (A) It revealed marked chronic inflmmation with lymphoid aggregation and blunting of villi (H&E, ×100). (B) It revealed lymphoid aggregation and villous atrophy (H&E, ×400).

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