Simultaneous Occurrence of Gallbladder Cancer in a Laundry Couple: Association between Gallbladder Cancer and Benzene

Kwang Yeun Shim; Sang-Woo Cha; Wook Hyun Um; Chang Gyun Chun; Soung Won Jeong; Jae Young Jang; Young Deok Cho

doi:10.4166/kjg.2013.61.2.107

Journal List > Korean J Gastroenterol > v.61(2) > 1007054

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Shim, Cha, Um, Chun, Jeong, Jang, and Cho: Simultaneous Occurrence of Gallbladder Cancer in a Laundry Couple: Association between Gallbladder Cancer and Benzene

Case Report

Korean J Gastroenterol 2013;61(2):107-109.

Published online: 4 October 2013

DOI: https://doi.org/10.4166/kjg.2013.61.2.107

Simultaneous Occurrence of Gallbladder Cancer in a Laundry Couple: Association between Gallbladder Cancer and Benzene

Kwang Yeun Shim, Sang-Woo Cha, Wook Hyun Um, Chang Gyun Chun, Soung Won Jeong, Jae Young Jang, Young Deok Cho

Institute for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea

Correspondence to: Young Deok Cho, Institute for Digestive Research, Digestive Disease Center, Department of Internal Medicine, Soonchunhyang University College of Medicine, 59 Daesagwan-ro, Yongsan-gu, Seoul 140-743, Korea. Tel: +82-2-709-9581, Fax: +82-2-709-9696, E-mail: ydcho@schmc.ac.kr

Received 27 April 20125 July 2012 Accepted 13 July 2012

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Gallbladder (GB) cancer occurs predominately as a biliary tract malignant tumor. It generally has a very poor prognosis, and early detection is often difficult. A variety of carcinogens have been implicated as an important cause for GB cancer. Benzene is a well-known carcinogen for hematologic malignancy, and its casual relationship with GB cancer has been suggested. We report a case of two patients who had operated a laundry cleaning facility together and later simultaneously got GB cancer after prolonged benzene exposure.

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Keywords: Gallbladder neoplasms, Benzene

References

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Fig. 1.

Abdominal CT finding of first patient (husband). A 6×7 cm sized hypoechoic mass lesion (arrow) in gallbladder and infiltration into the liver parenchyma.

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Fig. 2.

CT finding of second patient (wife). A 2×2 cm sized mass lesion (arrow) in the gallbladder body with enhanced wall thickening.

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