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Kim, Kim, Yoon, Jun, Lee, Kim, Kim, and Lee: A Case of Colonic Collision Tumor (Adenocarcinoma and Neuroendocrine Carcinoma)
Case Report
The Korean Journal of Gastroenterology

The Korean Journal of Gastroenterology 2012; 60(5): 325-329.

Published online: 22 November 2012

DOI: https://doi.org/10.4166/kjg.2012.60.5.325

A Case of Colonic Collision Tumor (Adenocarcinoma and Neuroendocrine Carcinoma)

Dong Wan Kim, Sang Hyun Kim, Jong Min Yoon, Tae Yung Jun, Su Jin Lee, Yang Jin Kim, Ho Yung Kim1, Jin Sook Lee2

Department of Internal Medicine, Good Samsun Hospital, Busan, Korea.

1Department of Surgery, Good Samsun Hospital, Busan, Korea.

2Department of Pathology, Good Samsun Hospital, Busan, Korea.

Correspondence to: Sang Hyun Kim, Department of Internal Medicine, Good Samsun Hospital, 326 Gaya-daero, Sasang-gu, Busan 617-718, Korea. Tel: +82-51-310-9122, Fax: +82-51-323-3308, enbd100@korea.com

Received 17 September 2011       Revised 11 October 2011       Accepted 12 October 2011

Copyright © 2012 The Korean Society of Gastroenterology

(open-access):

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Collision tumors of the colon are rare. A 54-year-old man was referred to our hospital for the evaluation of hematochezia. Colonoscopy demonstrated the presence of about 3 cm sized mass in the rectosigmoid junction. After surgical resection, the colonic lesion was histologically composed of two discrete lesions: adenocarcinoma in the superficial layer and poorly differentiated neuroendocrine carcinoma in the deeper layer. We report this case of colonic collision tumor (adenocarcinoma and neuroendocrine carcinoma) with a review of the literature.

Keywords: Collision tumor, Neuroendocrine carcinoma, Adenocarcinoma, Colon

Figures and Tables

Fig. 1
Colonoscopic finding. It showed about 3 cm sized ulcerofungating mass in the rectosigmoid junction.
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Fig. 2
Abdominal CT finding. An about 3 cm sized intraluminal enhancing mass was seen on the rectosigmoid junction without streaky densities in surrounding pericolic fat tissue.
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Fig. 3
Laparoscopic finding. It showed serosal infiltration of the mass in the rectosigmoid junction (arrowheads).
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Fig. 4
Pathologic findings. (A) Adenocarcinoma (left) and neuroendocrine carcinoma (right) were juxtaposed with no evidence of transition or admixture (H&E, ×200). (B, C) Neuroendocrine carcinoma showed cytoplasmic immunoreactivity for synaptophysin and CD56 (×400).
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Fig. 5
Abdominal CT and PET-CT findings after adjuvant chemotherapy. (A) Abdominal CT showed pericolic fatty infiltration and mild wall thickening of the sigmoid colon (arrow). (B) PET-CT showed focal hot spot at the sigmoid mesocolonic area, abutting on prior operative site (arrow).
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Notes

Financial support: None.

Conflict of interest: None.

References

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