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Choi, Suh, Park, Lee, Lee, Choi, Park, and Hong: The Prevalence of Barrett's Esophagus and the Comparison of Barrett's Esophagus with Cardiac Intestinal Metaplasia in the Health Screening at a Secondary Care Hospital
Original Article
Alimentary Tract
The Korean Journal of Gastroenterology

The Korean Journal of Gastroenterology 2012; 60(4): 219-223.

Published online: 20 October 2012

DOI: https://doi.org/10.4166/kjg.2012.60.4.219

The Prevalence of Barrett's Esophagus and the Comparison of Barrett's Esophagus with Cardiac Intestinal Metaplasia in the Health Screening at a Secondary Care Hospital

Cheul Young Choi, Seungchul Suh, Jae Serk Park, Hyun Jeong Lee, Jong Sup Lee, Hyo Sun Choi, Hyun Sung Park, Seung Goun Hong

Department of Internal Medicine, SAM Anyang Hospital, Anyang, Korea.

Correspondence to: Seung Goun Hong, Department of Internal Medicine, SAM Anyang Hospital, 9 Samdeok-ro, Manan-gu, Anyang 430-733, Korea. Tel: +82-31-467- 9114, Fax: +82-31-449-0151, permi@naver.com

Received 19 March 2012       Revised 25 April 2012       Accepted 7 May 2012

Copyright © 2012 The Korean Society of Gastroenterology

(open-access):

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background/Aims

The purpose of this study was to estimate the prevalence of Barrett's esophagus (BE) and its association with reflux esophagitis (RE) and peptic ulcer disease detected by free charge endoscopy which was covered by the National Health Insurance at a secondary care hospital, and to compare the results of the biopsy of BE with that of cardiac intestinal metaplasia (CIM).

Methods

A total of 4,002 patients underwent endoscopy from March 2010 to December 2012. BE was diagnosed if there was histologically proven specialized intestinal metaplasia, and CIM was diagnosed if intestinal metaplasia was accompanied with chronic gastritis.

Results

Four hundred twenty four patients underwent endoscopic biopsy, and the prevalence of BE was 1.0% (42/4,002). The mean age and the proportion of males in BE were significantly higher than those of the rest of study population, and BE had slight tendency related to RE than the rest of study population. CIM was observed in 34 patients and BE and CIM showed similar results, regarding age, sex and association with RE. The mean length of endoscopic Barrett's mucosa of BE group was 9.2±5.1 mm, and it was similar to that of CIM.

Conclusions

The prevalence of BE in the secondary care hospital was not low, and old age and male sex were significantly associated with BE. Because BE was observed in about 10% of biopsied patients and CIM was observed in a similar percentage with BE, the precise targeted biopsy is warranted and the biopsy method should be reestablished through the large prospective study of multiple secondary care hospitals.

Keywords: Barrett, Prevalence, Cardia, Metaplasia, Free

Figures and Tables

Table 1
Comparison between the Intestinal Metaplasia Group and the Non-Intestinal Metaplasia Group
kjg-60-219-i001

Values are presented as mean±SD or n (%).

IM, intestinal metaplasia; GERD, gastroesophageal reflux disease; GU, gastric ulcer; DU, duodenal ulcer.

Table 2
Comparison between the Barrett's Esophagus Group and the Cardiac Intestinal Metaplasia Group
kjg-60-219-i002

Values are presented as mean±SD or n (%).

BE, Barrett's esophagus; CIM, cardiac intestinal metaplasia; GERD, gastroesphageal reflux disease; LA, Los Angeles Classification; GU, gastric ulcer; DU, duodenal ulcer.

Table 3
Prevalence of Barrett's Esophagus in Relation to Age Distribution
kjg-60-219-i003

Values are presented as n (%).

Table 4
Comparison between the Intestinal Metaplasia Group and the Non-intestinal Metaplasia Group according to the Length of the Endoscopic Barrett's Mucosa
kjg-60-219-i004

Values are presented as number or mean±SD.

IM, intestinal metaplasia; BE, Barrett's esophagus; CIM, cardiac intestinal metaplasia.

Comparison abetween BE with CIM, bbetween IM with non-IM, cbetween BE with CIM and non-IM.

Notes

Financial support: None.

Conflict of interest: None.

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