Malignant Solitary Fibrous Tumor of Retroperitoneum Mimicking Gastric Submucosal Tumor

Jung Min Bae; Se Won Kim; Sang Woon Kim; Sun Kyo Song

doi:10.4166/kjg.2011.57.1.47

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Bae, Kim, Kim, and Song: Malignant Solitary Fibrous Tumor of Retroperitoneum Mimicking Gastric Submucosal Tumor

Case Report

Korean J Gastroenterol 2011;57(1):47-50.

Published online: 4 October 2011

DOI: https://doi.org/10.4166/kjg.2011.57.1.47

Malignant Solitary Fibrous Tumor of Retroperitoneum Mimicking Gastric Submucosal Tumor

Jung Min Bae, Se Won Kim, Sang Woon Kim, Sun Kyo Song

Department of Surgery, Yeungnam University College of Medicine, Daegu, Korea

Correspondence to: Sang Woon Kim, Department of Surgery, Yeungnam University College of Medicine, 317-1, Daemyung-dong, Namgu, Daegu 705-030, Korea. Tel: +82-53-620-3580, Fax: +82-53-624-1213, E-mail: swkim@med.yu.ac.kr

Received 26 January 2010 Revised 7 May 2010 Accepted 7 May 2010

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Solitary fibrous tumors (SFTs) are an uncommon neoplasm characterized by the proliferation of spindle cells. The diagnostic criteria of malignant solitary fibrous tumors (MSFTs) include high cellularity, high mitotic activity (4＞10 HPF), pleomorphism, hemorrhage and necrosis. This tumor frequently involves the pleura and MSFTs of retroperitoneum mimicking gastric submucosal tumor are very rare. We report a rare case of MSFT that presented as a gastric submucosal tumor. A gastroscopic examination showed a large bulging mucosa in the gastric body. Abdominal computed tomography revealed a well-defined heterogeneous enhancing mass between the left hepatic lobe and gastric body. Surgical resection was performed and histologic features were consistent with a MSFT.

Keywords: Malignant solitary fibrous tumor, Retroperitoneum, Gastric submucosal tumor

References

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Fig. 1.

Gastroscopic finding showed huge bulging mucosa in the lesser curvature side of the gastric body.

Fig. 2.

Abdominal CT findings. (A) Non-contrast abdominal CT showed a heterogenous mass like lesion (white arrow). (B) Contrast abdominal CT showed a well-defined heterogeneous enhancing mass, about 10 cm in size between the left hepatic lobe and the lesser curvature side of the gastric body (white arrow).

Fig. 3.

Gross appearance of cut surface showed yellowish white solid mass with focal area of cystic change and necrosis (white arrow). The tumor was 22.0×12.0×5.0 cm in size.

Fig. 4.

Histopathologic findings. (A) This histopathologic features were consistent with spindle shaped cells (H&E, ×200), (B) The tumor cells showed strong positive staining for CD34 (×200), (C) The tumor cells showed strong positive staining for Bcl-2 (×200),(D) The tumor cells showed focally weak positive staining for CD99 (×200).

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