A Case of Superior Mesenteric Venous Thrombosis Due to Protein C Deficiency in a Patient with Duodenal Ulcer Bleeding

Jae Gon Woo; Ji Eun Lee; Oh Un Kwon; Kyoung Won Jung; Chang Wook Jung; Dae Hyeon Cho; Kil Jong Yu; Sang Goon Shim

doi:10.4166/kjg.2011.57.1.34

Journal List > Korean J Gastroenterol > v.57(1) > 1006820

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Woo, Lee, Kwon, Jung, Jung, Cho, Yu, and Shim: A Case of Superior Mesenteric Venous Thrombosis Due to Protein C Deficiency in a Patient with Duodenal Ulcer Bleeding

Case Report

Korean J Gastroenterol 2011;57(1):34-37.

Published online: 4 October 2011

DOI: https://doi.org/10.4166/kjg.2011.57.1.34

A Case of Superior Mesenteric Venous Thrombosis Due to Protein C Deficiency in a Patient with Duodenal Ulcer Bleeding

Jae Gon Woo, Ji Eun Lee, Oh Un Kwon, Kyoung Won Jung, Chang Wook Jung, Dae Hyeon Cho, Kil Jong Yu, Sang Goon Shim

Department of Internal Medicine, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, Masan, Korea

Correspondence to: Dae Hyeon Cho, Department of Internal Medicaine, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, 50, Hapsung 2-dong, Masan 630-723, Korea. Tel: +82-55-290-6841, Fax: +82-55-290-6400, E-mail: meddrcho@hanmail.net

Received 13 January 2010 Revised 2 April 2010 Accepted 6 April 2010

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mesenteric venous thrombosis is a clinically very rare disease, and may cause bowel infarction and gangrene. Difficulty in the dignosis the disease due to its non-specific symptoms and low prevalence can cause a clinically fatal situation. Mesenteric venous thrombosis may be caused by both congenital and acquired factors, and protein C deficiency, which is a very rare genetic disorder, is one of many causes of mesenteric thrombosis. The authors experienced a case of mesenteric venous thrombosis caused by protein C deficiency in a patient with duodenal ulcer bleeding, so here we report a case together with literature review.

Keywords: Mesenteric venous thrombosis, Protein C deficiency, Mesenteric vascular disease

References

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Fig. 1.

Endoscopic findings of duodenum. (A) An oval shape ulcer with active bleeding was seen at the duodenal bulb. (B) Hemostasis was done using argon plasma coagulation.

Fig. 2.

Contrast-enhanced abdominal CT findings. Intraluminal thrombus (arrow) was present in the dilated superior mesenteric vein. Bowel edema was not observed.

Fig. 3.

Follow-up contrast-enhanced abdominal CT finding. Eight weeks after treatment, it showed complete resolution of previous mesenteric venous thrombosis (arrow).

Fig. 4.

Follow-up endoscopic finding of the duodenum. Eight weeks after treatment, an ulcer scar was seen at the duodenal bulb.

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