Primary Malignant Melanoma of the Esophagus

Sang Gyun Kim

doi:10.4166/kjg.2011.57.4.262

Journal List > Korean J Gastroenterol > v.57(4) > 1006801

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Kim: Primary Malignant Melanoma of the Esophagus

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Korean J Gastroenterol 2011;57(4):262-264.

Published online: 4 October 2011

DOI: https://doi.org/10.4166/kjg.2011.57.4.262

Primary Malignant Melanoma of the Esophagus

Sang Gyun Kim

Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea

Correspondence to: Sang Gyun Kim, Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul 110-799, Korea. Tel: +82-2-740-8112, Fax: +82-2-743-6701, E-mail: harley1333@hanmail.net

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

References

1. Stranks GJ, Mathai JT, Rowe-Jones DC. Primary malignant melanoma of the oesophagus: case report and review of surgical pathology. Gut. 1991; 32:828–830.

2. Li B, Lei W, Shao K, et al. Characteristics and prognosis of primary malignant melanoma of the esophagus. Melanoma Res. 2007; 17:239–242.

3. Chalkiadakis G, Wihlm JM, Morand G, Weill-Bousson M, Witz JP. Primary malignant melanoma of the esophagus. Ann Thorac Surg. 1985; 39:472–475.

4. Simpson NS, Spence RA, Biggart JD, Cameron CH. Primary malignant melanoma of the oesophagus. J Clin Pathol. 1990; 43:82–83.

5. Uetsuka H, Naomoto Y, Fujiwara T, et al. Primary malignant melanoma of the esophagus: long-term survival following pre- and postoperative adjuvant hormone/chemotherapy. Dig Dis Sci. 2004; 49:1646–1651.

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Fig. 1.

Endoscopic and EUS finding. (A)3 cm sized polypoid mass with central black pigmentation was noted in mid-esophagus. (B) Segmental wall thickening with submucosal invasion was observed.

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Fig. 2.

Gross and microscopic finding. (A) 4.5 cm sized black polypoid mass was noted in resected esophagus. (B) Black-pigmented esophageal melanoma was seen. (C) A dense proliferation of epithelioid and spindle-shaped cells was observed beneath the epithelium (H&E, ×400).

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Fig. 3.

Whole body PET showed multiple hypermetabolic uptakes in mediastinal lymph nodes, paravertebral area and ribs.

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