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Abstract
Background/Aims
Endoscopic retrograde cholangiopancreatograpy (ERCP) is often used for the diagnosis and treatment of pancreaticobiliary diseases in the elderly patients. However, few studies have assessed its efficacy and safety in the very elderly. The purpose of this study was to evaluate the clinical outcomes of ERCP in the very elderly patients.
Methods
Eight hundreds two patients who underwent ERCP at Seoul National University Bundang hospital were enrolled retrospectively. They were divided into three groups according to their ages (non-elderly group, elderly group and very-elderly group; <65, 65–79 and ≥80, respectively). The indications and clinical outcomes including the complications of ERCP were compared among groups.
Results
The most common indication of ERCP was acute cholangitis in all the three groups. Periampullary diverticulum was more frequently observed in elderly and very-elderly patients than in younger patients. Mean duration of hospitalization was not different among three groups. ERCP success rate in all enrolled patients was approximately 90%, and there was no difference in terms of technical success rate between groups (p=0.1). However, the number of ERCP sessions was significantly higher in the very-elderly patients compared to in the non-elderly and elderly (1.38 vs. 1.13 and 1.18 respectively; p<0.001). There was no difference in mortality and complication rate between groups.
References
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Table 1.
Baseline Characteristics and Concomitant Chronic Diseases in Three Groups
Table 2.
The Indications of ERCP according to Different Age Groups
| Non-elderly (n=382) | Elderly (n=330) | Very-elderly (n=90) | p-value | |
|---|---|---|---|---|
| Acute cholangitis | 261 (68.3%) | 194 (58.8%) | 66 (73.3%) | 0.561 |
| Pancreatitis | 19 (5.0%) | 18 (5.5%) | 0 (0%) | 0.168 |
| Pancreaticobiliary cancer | 52 (13.6%) | 75 (22.7%) | 19 (21.1%) | 0.006 |
| Others a | 50 (13.1%) | 43 (13.0%) | 5 (5.6%) | 0.137 |
Table 3.
Clinical Outcomes of ERCP according to Different Age Groups
Table 4.
Complications and Mortality of ERCP according to Different Age Groups
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