Intestinal Thrombotic Microangiopathy after Liver Transplantation

Eun Ran Kim; Kyoung Mee Kim

doi:10.4166/kjg.2011.57.3.198

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Kim and Kim: Intestinal Thrombotic Microangiopathy after Liver Transplantation

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Korean J Gastroenterol 2011;57(3):198-200.

Published online: 4 October 2011

DOI: https://doi.org/10.4166/kjg.2011.57.3.198

Intestinal Thrombotic Microangiopathy after Liver Transplantation

Eun Ran Kim, Kyoung Mee Kim¹

¹Departments of Medicine and Pathology, Seoul, Korea

Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Correspondence to: Kyoung Mee Kim, Department of Pathology, Sungkyunkwan University School of Medicine, 50, Irwon-dong, Gangnam-gu, Seoul 135-710, Korea. Tel: +82-2-3410-2800, Fax: +82-2-3410-0025, E-mail: kkmkys@skku.edu

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

References

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8. Takatsuka H, Wakae T, Mori A, et al. Endothelial damage caused by cytomegalovirus and human herpesvirus-6. Bone Marrow Transplant. 2003; 31:475–479.

9. Yamamoto S, Nakase H, Chiba T, Yamashita K, Ito M. Clinical challenges and images in GI. Image 4. Transplant-associated thrombotic microangiopathy of the colon accompanied by graft-versus-host disease. Gastroenterology. 2009; 136:2067–2418.

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12. Komeno Y, Ogawa S, Ishida T, et al. Ischemic colitis as a manifestation of thrombotic microangiopathy following bone marrow transplantation. Intern Med. 2003; 42:1228–1232.

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Fig. 1.

Colonoscopic findings in the descending colon (A) and sigmoid colon (B) showed longitudinal ulcerations and erythematous mucosal changes which mimicked ischemic colitis.

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Fig. 2.

Pathologic findings of colon biopsy. (A) It showed denuded mucosa with mucosal congestion and hemorrhage (H&E, ×100) (B) with micro-thrombi (arrows) in capillaries with swollen and detached endothelial cells (H&E, ×400).

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