A Case of Large Retroperitoneal Lipoma Mimicking Liposarcoma

Kyoung Rok Lee; Tae Jin Seo; Jun Ho Cho; Hyung Il Kim; Young Hoi Hur; Sung Bum Cho; Wan Sik Lee; Young Eun Joo

doi:10.4166/kjg.2010.55.6.394

Journal List > Korean J Gastroenterol > v.55(6) > 1006679

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Lee, Seo, Cho, Kim, Hur, Cho, Lee, and Joo: A Case of Large Retroperitoneal Lipoma Mimicking Liposarcoma

Original Article

Korean J Gastroenterol 2010;55(6):394-398.

Published online: 21 February 2010

DOI: https://doi.org/10.4166/kjg.2010.55.6.394

A Case of Large Retroperitoneal Lipoma Mimicking Liposarcoma

Kyoung Rok Lee, M.D., Tae Jin Seo, M.D., Jun Ho Cho, M.D., Hyung Il Kim, M.D., Young Hoi Hur, M.D.^∗, Sung Bum Cho, M.D., Wan Sik Lee, M.D., Young Eun Joo, M.D.

Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea

^∗Department of General Surgery, Chonnam National University Medical School, Gwangju, Korea

Correspondence to: Young Eun Joo, M.D. Department of Internal Medicine, Chonnam National University Hwasun Hospital, 160, Ilsim-ri, Hwasun-eup, Hwasun, Jeonnam 519-809, Korea Tel: +82-61-379-7603, Fax: +82-61-379-7628 E-mail: yejoo@chonnam.ac.kr

Received 1 September 2009 Accepted 25 February 2010

Abstract

Lipomas are the most common benign tumors of adipose tissue among adults. Lipomas can occur almost any-where in the trunk, extremities, mediastinum, and pelvis, but retroperitoneal lipomas are extremely rare. It should be distinguished from well differentiated liposarcoma in order to provide the appropriate treatment and follow up. We experienced a case of 60-year-old patient with large retroperitoneal lipoma mimicking liposarcoma causing palpable abdominal mass and pain. Abdominal computerized tomography (CT) showed 33×22 cm sized bulky fat-containing mass with contrast enhanced solid portion in right retroperitoneum. Positron emission tomograpgy (PET) revealed increased 18F-FDG uptake at solid portion shown in abdominal CT. Imaging studies confirmed a high index of suspicion on liposarcoma. Laparotomy showed a large encapsulating tumor arising from retroperitoneum with fat necrosis. Pathologic examination of resected specimen revealed normal mature adipocytes without atypical cells, compatible with lipoma.

Keywords: Retroperitoneum, Lipoma, Liposarcoma, Fat necrosis

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Fig. 1.

Abdominal CT finding showed a large fat-containing mass with contrast enhanced solid portion (arrow) in abdominal cavity.

Fig. 2.

PET finding of abdomen showed increased 18F-FDG uptake (arrow) at solid portion shown in abdominal CT.

Fig. 3.

Gross morphology of specimen. (A) The large encapsulated yellowish mass with septation originated in retroperitoneal cavity was observed. (B) The yellowish mass was divided into 7 pieces of encapsulated materials.

Fig. 4.

Microscopic finding of resected specimen. (A) The lesion was composed of dense normal mature adipocytes (H&E stain, ×40). (B) Necrotic stroma was accompanied by normal mature adipocytes (H&E, ×100).

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