Journal List > Korean J Gastroenterol > v.55(3) > 1006641

Ahn, Han, Park, Kim, Eun, Jeon, and Sohn: A Case of Segmental Colitis Associated with Diverticular Disease

Abstract

Segmental colitis associated with diverticular disease (SCAD) is a colonic inflammatory disorder with localized non-granulomatous inflammation at sigmoid colon, and associated with colonic diverticulosis. SCAD is an appa-rently uncommon disorder in Western. We experienced a rare case of SCAD in a 46-year-old woman who visited the hospital due to abdominal discomfort. Colonoscopic examination showed multiple sigmoid diverticula in association with a segment length colitis. Colonoscopic biopsies of the sigmoid colon demonstrated cryptitis and crypt abscess along with chronic inflammatory cells infiltration. The biopsies of the rectum was histologically normal. The patient was given the diagnosis of SCAD and treated with oral mesalamine. This is the first case of SCAD reported in Korea.

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Fig. 1.
Colonoscopic findings. It showed disappearance of the vascular reticulum associated with edema, erythema, and friability in 5- cm segment of sigmoid colon. Di-verticuli were seen in the region of segment colitis (A, B, C). Rectal mucosa was spared (D) (arrow: di-verticuli).
kjg-55-189f1.tif
Fig. 2.
Histologic findings of endoscopic biopsy specimen of sigmoid colon. It showed scattered mononuclear cell, neutophils, and acute cyptitis with crypt abscess formation (A: H&E, ×200, B: H&E, ×400).
kjg-55-189f2.tif
Fig. 3.
Follow-up colonoscopic findings. (A) Mild erythema of diverticular opening in the cecum (arrow). (B, C) The disappearance of the vascular reticulum associated with edema, erythema, and friability in 5-cm segment of sigmoid colon. (D) Rectal mucosa was spared.
kjg-55-189f3.tif
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