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Park, Cho, Lee, Shin, Choi, Lee, and Paik: Sarcomatoid squamous cell carcinoma of uterine cervix
Case Report
Korean Journal of Obstetrics and Gynecology

Korean Journal of Obstetrics and Gynecology 2010; 53(10): 946-951.

Published online: 31 October 2010

DOI: https://doi.org/10.5468/kjog.2010.53.10.946

Sarcomatoid squamous cell carcinoma of uterine cervix

Young Park, M.D.1, Jee Hae Cho, M.D.1, Jong Sil Lee, M.D.2, 3, Jeong Kyu Shin, M.D.1, 2, Won Jun Choi, M.D.1, 2, Jong Hak Lee, M.D.1, 2, Won Young Paik, M.D.1, 2

1Department of Obstetrics and Gynecology, Gyeongsang National University School of Medicine, Jinju, Korea.

2Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.

3Department of Pathology, Gyeongsang National University School of Medicine, Jinju, Korea.

Corresponding author (wypaik@gnu.ac.kr)

Received 20 May 2010       Revised 30 July 2010       Accepted 6 September 2010

Copyright © 2010 Korean Society of Obstetrics and Gynecology

Abstract

Sarcomatoid squamous cell carcinoma (SSCC) is composed of squamous cell carcinoma element and spindle cell element, and can occur in any organ, such as the lung, skin and esophagus. But SSCC in uterine cervix is very rare. The prognosis of SSCC is poorer than squamous cell carcinoma (SCC) of uterine cervix. We report here a case of SSCC of uterine cervix with a brief review of literature.

Keywords: Sarcomatoid squamous cell carcinoma, Uterine cervix

Figures and Tables

Fig. 1
Pelvis CT showed the LN enlargement at Lt. iliac area (arrow) and ill-defined cervical mass.
kjog-53-946-g001
Fig. 2
(A) The tumor consists of squamous cell carcinoma (solid arrows). (B) Sarcomatoid component (open arrows) (H&E stain, ×100).
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Fig. 3
Lymph node involvement by squamous cell carcinoma component (arrows heads) (H&E stain, ×100).
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Fig. 4
Immunoperoxidase staining for cytokeratin (A) and vimentin (B). (A) The squamous cell carcinoma component (solid arrows) and sarcomatoid component (open arrows) was positive for cytokeratin (×200). (B) The sarcomatoid component (open arrows) was positive for vimentin (×200).
kjog-53-946-g004
Fig. 5
(A) Four-month postoperative CT scan showed a mass of 5.4 cm in diameter extended from vaginal stump to pelvic cavity (A) and hydronephrosis of right kidney due to pelvic mass (B). (B) There were right hydronephrosis (arrow) due to right pelvic mass.
kjog-53-946-g005
Table 1
Cases of sarcomatoid squamous cell carcinoma in uterine cervix
kjog-53-946-i001

FIGO: International Federation of Gynecology and Obstetrics, DOD: died of disease, ERBT: external-beam radiotherapy, RAH: radical abdominal hysterectomy, CRS: cytoreductive therapy, NR: not reported.

References

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