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Kim, Han, Kim, and Jun: Transient newborn neutropenia immediately after chemotherapy during pregnancy: A case report
Case Report
Korean Journal of Obstetrics and Gynecology

Korean Journal of Obstetrics and Gynecology 2010; 53(9): 833-837.

Published online: 30 September 2010

DOI: https://doi.org/10.5468/kjog.2010.53.9.833

Transient newborn neutropenia immediately after chemotherapy during pregnancy: A case report

Eun-Na Kim, M.D., Kyung Hee Han, M.D., Su Ah Kim, M.D., Jong Kwan Jun, M.D.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

Corresponding author (jhs0927@snu.ac.kr)

Received 31 May 2010       Accepted 6 July 2010

Copyright © 2010 Korean Society of Obstetrics and Gynecology

Abstract

The incidence of acute leukemia in pregnancy is as low as 1 in 75,000 pregnancies. There is no established guideline for the treatment of leukemia during midtrimester pregnancy. But nowadays, consensus is not to delay the leukemia treatment with chemotherapy even in pregnancy. Many authors reported successful outcomes of mothers and newborns. Because of the leukemia itself and side effects of the chemotherapy, anemia, thrombocytopenia and neutropenia are commonly encountered in women treated with chemotherapy. With chemotherapy in utero just before the delivery, the newborn could be neutopenic. We report one case of midtrimester pregnant woman who took chemotherapy for leukemia and suffered from neutropenic fever and preterm labor. The newborn was neutropenic. However, both the mother and the baby were successfully recovered from neutropenia.

Keywords: Pregnancy, Acute leukemia, Chemotherapy, Newborn, Neutropenia

Figures and Tables

Figure 1
Newborn absolute neutrophil count (ANC): newborn neutropenia after chemotherapy in utero was recovered with granulocyte colony stimulating factor.
kjog-53-833-g001

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