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Lee, Kim, Kim, Joo, Jun, Han, Koo, Kim, Chun, and Cho: Adenomatoid tumors of female genital tracts:An analysis of 195 cases
Original Article
Korean Journal of Obstetrics and Gynecology

Korean Journal of Obstetrics and Gynecology 2010; 53(8): 714-719.

Published online: 17 September 2010

DOI: https://doi.org/10.0000/kjog.2010.53.8.714

Adenomatoid tumors of female genital tracts:An analysis of 195 cases

Ji Eun Lee, M.D.1, Mi La Kim, M.D.1, Joo Myoung Kim, M.D.1, Kwan Young Joo, M.D.1, Jong Young Jun, M.D.1, Ho Won Han, M.D.1, Yu Jin Koo, M.D.1, Yun Young Kim, M.D.1, Yi Kyeong Chun, M.D.2, Yeon Jean Cho, M.D.1

1Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.

2Department of Pathology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.

Address reprint requests to Yeon-Jean Cho, MD. Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine, Seoul, Korea.jeanjane@naver.com

Received 19 March 2010       Accepted 11 June 2010

Copyright © Korean Society of Obstetrics and Gynecology

Abstract

Purpose

Adenomatoid tumors of female genital tracts are benign lesions derived from mesothelium, occurring most commonly during the reproductive years. The aim of this study was to evaluate the overall incidence of adenomatoid tumors in Korean women and to analyze the clinical characteristics.

Methods

One hundred and ninety five patients with adenomatoid tumors were found in a retrospective medical records review of pathologic reports for 44,984 benign uterine diseases at Cheil General Hospital, from January 1995 to April 2009.

Results

The overall incidence rate was 0.42% of all benign uterine disease. Among them, 149 patients received hysterectomy, and 46 patients received uterine conservative surgery. Main symptoms of the patients were pain (25.1%), bleeding (30.2%), and palpable mass (18.5%). Most common associated pathologies were leiomyoma (46.6%), adenomyosis (25.1%) and endometriosis (13.1%). Most of the diagnosis was made postoperatively. Among 46 patients with conservative treatment, 13 patients showed successful pregnancy outcome. No recurrence occurred during the follow up period.

Conclusions

Adenomatoid tumors are associated with fibroids and tend to mimic them clinically, making pre.operative diagnosis difficult. The recurrence is rare even after conservative operation. Our data about this benign neoplasm may be helpful for counseling patients after operations.

Keywords: Adenomatoid tumor, Female genital tract, Mesothelioma

Figures and Tables

Figure 1
Solid cords or variable sized cystic spaces lined by flat to cuboidal tumor cells (H&E stain, ×100).
kjog-53-714-g001
Figure 2
Immunohistochemical stain for calretinin showing diffuse strong positivity in tumor cells (×100).
kjog-53-714-g002
Table 1
Characteristics of patients according to operation methods
kjog-53-714-i001
Table 2
Indication for operation according to operation methods
kjog-53-714-i002
Table 3
Coexisting pathologies with adenomatoid tumor
kjog-53-714-i003

All of the associated pathologies were recorded together.

Table 4
Pregnancy outcome after conservative management of adenomatoid tumor
kjog-53-714-i004

Op.: operation, OI: ovulation induction, IVF: in vitro fertilization, IIOC: incompetent internal os of cervix, C/S: cesarean section, NSVD: normal spontaneous vaginal delivery.

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