Journal List > Korean J Urol > v.50(8) > 1005389

Kim, Jeon, Yang, and Han: Tumor Exposure and Cold Ischemia Using a LapSac® in Partial Nephrectomy by Video-Assisted Minilaparotomy Surgery (VAMS)

Abstract

Purpose

We report a new method of tumor exposure through a minilaparotomy window and cold ischemia using a LapSac during partial nephrectomy by video-assisted minilaparotomy surgery (VAMS).

Materials and Methods

Partial nephrectomy was performed by VAMS in a total of 31 patients during a period ranging from January 2004 to June 2006, and tumor exposure and cold ischemia were achieved by using a LapSac. We investigated the tumor size and location, mean operative time, mean estimated blood loss, mean cold ischemic time, and pathologic outcomes retrospectively. We evaluated preoperative and postoperative renal function with the estimated creatinine clearance rate by the MDRD equation.

Results

The mean tumor size was 2.59±1.30 cm and mean surgical time was 182.5±44.5 minutes. Mean cold ischemic time was 31.84±8.43 minutes. Mean estimated blood loss was 445.65±202.77 ml (range, 100-800 ml), and 3 patients required transfusion. A histopathologic examination confirmed a diagnosis of renal cell carcinoma in 22 patients (71%). The surgical margin was positive in 1 patient. Twenty-one patients had a mean followup of 53±8.19 months. Nineteen patients survived without any disease recurrence, 1 patient survived with lung metastasis within 5 months, and 1 patient died of unrelated cause. There was no significant difference between the preoperative and postoperative estimated creatinine clearance rate by using the MDRD equation.

Conclusions

Tumor exposure and cold ischemia were attempted in a partial resection of the kidney by VAMS with a LapSac. This technique for partial nephrectomy by VAMS might be an effective, safe modality.

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Fig. 1.
Technique of renal tumor exposure and cold ischemia using the LapSac. After wrapping the kidney with the LapSac, Hem-o-Lock clipping was applied to the LapSac opening placed in the renal hilum. The LapSac was dissected in four parts, and an ice slush was placed in the LapSac. Tumor exposure was easily performed by using these four parts.
kju-50-774f1.tif
Table 1.
Features of patients and tumors
  Total (%)
Sex  
 Male 20 (65)
 Female 11 (35)
Age (years)  
 Range 27-81
 Mean±SD 52.75±13.44
Mean BMI (kg/m2) 23.87±2.93
Solitary kidney 1 (3)
Tumor size (cm):  
 Range 1.1-6.5
 Mean±SD 2.59±1.30
Laterality (right/left) 18/13 (58/42)
Tumor location  
 Upper/middle/lower 11/15/5 (36/48/16)
 Exophytic/endophytic 18/13 (58/42)

BMI: body mass index

Table 2.
Intraoperative and postoperative data
Operative time (min)  
 Range 105-340
 Mean±SD 182.5±44.5
Mean ischemic time (min) 31.84±8.43
EBL (ml)  
 Range 100-800
 Mean±SD 445.65±202.77
Mean estimated creatinine clearance (MDRD) (ml/min/1.73 m2)  
 Preoperative 78.48±19.02
 Postoperative 1 month (nadir) 71.35±14.31
Intraoperative complication  
 Transfusion 3 (9%)
Hospital stays (days)  
 Range 4-15
 Mean±SD 7±2.6

EBL: estimated blood loss

Table 3.
Pathological features and surgical outcomes in 31 patients who underwent partial nephrectomy
  Total (%)
Type  
 Renal cell cancer 22 (71)
  Clear cell 19
  Papillary 2
  Unclassified 1
 Benign 9 (29)
  Papillary neoplasia 2
  Renal calyceal diverticulum 1
  Angiomyolipoma 3
  Oncocytoma 3
Tumor stage  
 pT1aN0M0 17 (77)
 pT1bN0M0 3 (14)
 pT3aN0M0 2 (9)
Tumor grade  
 1 6 (27)
 2 8 (36)
 3 8 (36)
 4 0 (0)
Surgical margin  
 Negative 21 (95)
 Positive 1 (5)
Recurrence 1 (4.5)
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