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Park, Yoo, and Kim: The Oncologic and Functional Results of the Ileal W-neobladder with a Serous-lined Extramural Tunnel
Original Article
Korean Journal of Urology

Korean Journal of Urology 2008; 49(9): 797-803.

Published online: 30 September 2008

DOI: https://doi.org/10.4111/kju.2008.49.9.797

The Oncologic and Functional Results of the Ileal W-neobladder with a Serous-lined Extramural Tunnel

Hongzoo Park, Changhee Yoo1, Choung-Soo Kim

Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

1Department of Urology, University of Hanlym College of Medicine, Seoul, Korea.

cskim@amc.seoul.kr

Received 22 April 2008       Accepted 17 July 2008

Copyright © 2008 The Korean Urological Association

Abstract

Purpose

We wanted to analyze the oncologic and functional outcomes of radical cystectomy and creation of an orthotopic ileal neobladder with a serous-lined extramural tunnel.

Materials and Methods

There were 110 patients and 101 patients were male (mean age: 58.7 years, age range: 35-78 years). All these patients underwent radical cystectomy and creation of a ileal W-shaped neobladder with a serous-lined extramural tunnel, and all the procedures were done by one surgeon. The median period of follow-up was 28.9 (range: 6-95) months. The Assessing the patients' clinical history, physical examinations, complete laboratory tests, CT scans and bone scans were performed postoperatively for the evaluation of recurrence and complications. The voiding patterns of 77 patients of the 110 patients were surveyed.

Results

Five-year-overall survival was 56% and the median survival period was 66.1 months. The tumor recurrence rate was 39.1% (43 patients) and 21 (19.1%) patients died due to progression of cancer. The daytime and nighttime urinary continence rates at postoperative 1 year were 87% and 79%, respectively. Sixty three (81%) patients among the 77 patients had no voiding problems after the procedures. Nine patients still had severe incontinence and 5 patients still suffered from voiding difficulty. Renal functional deterioration developed in 3 patients (2.8%); however, no patients were on dialysis. Acute pyelonephritis was observed in 12 patients and recurrent pyelonephritis occurred in 6 patients. Ureter-ileal anastomosis site stricture was occurred in 5 renal units. No reflux from the ileal bladder into the ureter was observed.

Conclusions

Radical cystectomy and an orthotopic ileal neobladder using a serous-lined extramural tunnel for patients with invasive bladder cancer were effective and durable procedures in terms of the oncologic and functional outcomes.

Keywords: Bladder cancer, Serous-lined extramural tunnel, Orthotopic bladder substitution, Complications

Figures and Tables

Fig. 1
Kaplan-Meier overall survival curve of the patients who underwent radical cystectomy and orthotopic neobladder formation by an Abol-Enein and Ghoneim procedure.
kju-49-797-g001
Table 1
Patient characteristics and the pathologic profiles
kju-49-797-i001
Table 2
Early and late complications of the ileal W-shaped neobladder
kju-49-797-i002

*APN: acute pyelonephritis, †Azotemia: serum creatinine ≥2.0 ug/ml after operation

Table 3
Outcomes of the voiding pattern surveys
kju-49-797-i003

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