Primary Neuroendocrine Carcinoma of the Urethra

Jun Nyung Lee; Dong Woo Lee; Young Su Kim; Ghil Suk Yoon; Jae Soo Kim; Eun Sang Yoo; Bup Wan Kim

doi:10.4111/kju.2008.49.3.284

Journal List > Korean J Urol > v.49(3) > 1005081

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Lee, Lee, Kim, Yoon, Kim, Yoo, and Kim: Primary Neuroendocrine Carcinoma of the Urethra

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Korean J Urol 2008;49(3):284-286.

Published online: 17 January 2008

DOI: https://doi.org/10.4111/kju.2008.49.3.284

Primary Neuroendocrine Carcinoma of the Urethra

Jun Nyung Lee, Dong Woo Lee, Young Su Kim¹, Ghil Suk Yoon^1,, Jae Soo Kim, Eun Sang Yoo, Bup Wan Kim

^¹Departments of Urology and Pathology, School of Medicine, Kyungpook National University, Daegu, Korea

교신저자: 유은상 경북대학교병원 비뇨기과 대구광역시 중구 삼덕 2가 50번지 700-721 TEL: 053-420-5841, FAX: 053-421-9618, E-mail: uroyoo@knu.ac.kr

Revised 22 January 2008 Accepted 18 February 2008

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary neuroendocrine carcinomas are uncommon highly malignant tumors of the genitourinary tract, and they have a poor prognosis. We report here on a case of a primary neuroendocrine carcinoma of the urethra that developed after radical cystectomy and ileal conduit diversion for treating transitional cell carcinoma of the urinary bladder.

Keywords: Neuroendocrine carcinoma, Urethra

REFERENCES

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Fig. 1.

The computed tomography scan shows a 4x2.5cm sized well-demarcated cystic mass on the urethra.

Fig. 2.

(A) The tumor cells display a small, round to oval nucleus with scanty cytoplasm and hyperchromatic nuclei (H&E, x200). (B) The malignant cells show strong positive staining for chromogranin (Immunohistochemistry, x100). (C) The malignant cells show strong positive staining for cytokeratin (Immunohistochemistry, x100). (D) The malignant cells show strong positive staining for synaptophysin (Immunohistochemistry, x100).

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