Journal List > Korean J Urol > v.49(11) > 1005018

Yang, Yu, Sung, Chung, and Noh: The Effectiveness of Transurethral Resection of the Prostate Combined with High Power Potassium-titanyl-phosphate (KTP) Laser Vaporization for Patients with a Prostate Volume Greater than 45cc

Abstract

Purpose

We compared the effectiveness of transurethral resection of the prostate (TURP) with the effectiveness of high power potassium-titanyl-phosphate (KTP) laser vaporization combined with TURP in patients with a prostate volume over 45cc.

Materials and Methods

Between March 2004 and March 2007, we analyzed all the patients with a prostate volume over 45cc and who underwent TURP or KTP laser vaporization combined with TURP for treating symptomatic benign prostatic hyperplasia (BPH). The patients were divided into two groups (Group I: TURP: n=53, Group II: KTP laser vaporization combined with TURP: n=54). The initial evaluation included a digital rectal examination, urinalysis, determining the hemoglobin, electrolyte and prostate-specific antigen (PSA) levels, the International Prostate Symptom Score (IPSS), the quality of life (QoL), the maximum urine flow rate (Qmax), the postvoiding residual urine (PVR), transrectal ultrasonography (TRUS) and urodynamic study. The postoperative hemoglobin and electrolyte levels were checked promptly, and the total operation time, the foley indwelling period and the number of hospital days were recorded afterwards. The IPSS, QoL, Qmax, and PVR were evaluated at 1 and 3 months postoperatively.

Results

The baseline characteristics and postoperative outcomes of the two groups were similar. The total blood loss during operation was significantly lower in Group II (p=0.02).

Conclusions

KTP laser vaporization combined with TURP resulted in less blood loss than TURP and it provided a good operation field in those patients who have over 45cc of prostate. Thus, KTP laser vaporization combined with TURP is safer than performing only TURP.

Figures and Tables

Table 1
Baseline characteristics of the patients
kju-49-1007-i001

TURP: transurethral resection of the prostate, KTP: potassium titanyl phosphate, IPSS: International Prostate Symptom Score, PSA: prostate-specific antigen, QoL: quality of life, Qmax: maximalurinary flow rate, PVR: postvoiding residual volume, *: prostate volume measured by transrectal ultrasonography

Table 2
The postoperative outcomes and comparison of the IPSS, Qmax, QoL and residual urine values of the two groups
kju-49-1007-i002

IPSS: International Prostate Symptom Score, QoL: quality of life, Qmax: maximal urine flow rate, *: transurethral resection of the prostate (TURP), : potassium titanyl phosphate (KTP) laser vaporization + TURP

Table 3
Safety parameters of the two groups
kju-49-1007-i003

*: transurethral resection of the prostate (TURP), : potassium titanyl phosphate (KTP) laser vaporization + TURP

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