Journal List > Korean J Urol > v.48(6) > 1004948

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Kim, Park, Yang, In, Kim, Yang, Sung, Chung, Kim, and Kim: Renal Angiomyolipoma Partially Containing Epithelioid Component
Case Report
Korean Journal of Urology

Korean Journal of Urology 2007; 48(6): 655-658.

Published online: 30 June 2007

DOI: https://doi.org/10.4111/kju.2007.48.6.655

Renal Angiomyolipoma Partially Containing Epithelioid Component

Han Min Kim, Joon Myoung Park, Seung Wan Yang, Young Ho In, Min Gyun Kim, Won Jae Yang3, Luck Hee Sung, Jae Yong Chung, Hyun-Jung Kim1, Soo Hyun Kim2

Department of Urology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

1Department of Pathology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

2Department of Diagnostic Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

3Department of Urology, Soonchunhyang University College of Medicine, Seoul, Korea.

Corresponding author (chung90@sanggyepaik.ac.kr)

Received 27 March 2007       Accepted 11 April 2007

Copyright © 2007 The Korean Urological Association

Abstract

Epithelioid renal angiomyolipoma is a recently recognized pathologic variant of angiomyolipoma, which represents a more malignant course than a classical renal angiomyolipoma. We report a case of histologically proven renal angiomyolipoma. The patient presented with the symptoms and signs of spontaneous rupture of the kidney. On surgical exploration, the ruptured kidney with upper pole kidney mass was resected. The enlarged regional lymph nodes were also removed, which showed the same pathology.

Keywords: Epithelioid cells, Angiomyolipoma, Kidney

Figures and Tables

Fig. 1
The computed tomography (CT) pre-enhanced (A) and enhanced (B) images. A tumor contains fat and an enhancing solid portion. The high-attenuating material suggests hematoma, which is visible in the perirenal space.
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Fig. 2
An ill-defined fibrofatty mass (6.5×5.5×3cm) is located at the upper pole of the left kidney. The surrounding perirenal fat tissue contains a large number of blood clots.
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Fig. 3
The tumor is composed of a heterogenous populations of a mature fat tissue, spindle cells and thick walled vessels (H&E, ×100).
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Fig. 4
(A) The medium power view shows epithelioid tumor cells arising from the vessel (H&E, ×100). (B) HMB-45 immunostaining is focally positive in some epithelioid tumor cells (HMB-45, ×400).
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Fig. 5
The para-aortic lymph nodes showed an aggregation of spindle-to-ovoid tumor cells in the juxtacapsular area. However, the pericapsular sinus or intranodal structures are intact and not involved with tumor emboli. This supports that this is multifocality rather than true metastasis (H&E, ×100).
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