Abstract
Small cell carcinoma was first described in the lung, and extrapulmonary small cell carcinoma has been reported at sites throughout the body. Small cell carcinoma of the genitourinary tract has more commonly been reported to arise from the urinary bladder. Small cell carcinoma of the kidney is extremely rare, rapidly progressive and lethal. Most of the reported cases have occurred in relatively old age people. We report here on a case of primary small cell carcinoma of the kidney in a young male, and this was managed via radical nephrectomy and cisplatin-based chemotherapy.
References
1. Morgan LC, Grayson D, Peters HE, Clarke CW, Peters MJ. Lung cancer in New South Wales: current trends and the influence of age and sex. Med J Aust. 2000. 172:578–582.
2. Remick SC, Ruckdeschel JC. Extrapulmonary and pulmonary small-cell carcinoma: tumor biology, therapy and outcome. Med Pediatr Oncol. 1992. 20:89–99.
3. Levenson RM Jr, Ihde DC, Matthews MJ, Cohen MH, Gazdar AF, Bunn PA Jr, et al. Small cell carcinoma presenting as an extrapulmonary neoplasm: sites of origin and response to chemotherapy. J Natl Cancer Inst. 1981. 67:607–612.
4. Kim JH, Lee SH, Park J, Kim HY, Lee SI, Nam EM, et al. Extrapulmonary small-cell carcinoma: a single-institution experience. Jpn J Clin Oncol. 2004. 34:250–254.
5. Mackey JR, Au HJ, Hugh J, Venner P. Genitourinary small cell carcinoma: determination of clinical and therapeutic factors associated with survival. J Urol. 1998. 159:1624–1629.
6. Asmis TR, Reaume MN, Dahrouge S, Malone S. Genitourinary small cell carcinoma: a retrospective review of treatment and survival patterns at The Ottawa Hospital Regional Cancer Center. BJU Int. 2006. 97:711–715.
7. Gonzalez-Lois C, Madero S, Redondo P, Alonso I, Salas A, Angeles montalban M. Small cell carcinoma of the kidney: a case report and review of the literature. Arch Pathol Lab Med. 2001. 125:796–798.
8. Majhail NS, Elson P, Bukowski RM. Therapy and outcome of small cell carcinoma of the kidney: report of two cases and a systematic review of the literature. Cancer. 2003. 97:1436–1441.
9. Galanis E, Frytak S, Lloyd RV. Extrapulmonary small cell carcinoma. Cancer. 1997. 79:1729–1736.
10. Lo Re G, Canzonieri V, Veronesi A, Dal Bo V, Barzan L, Zancanaro C, et al. Extrapulmonary small cell carcinoma: a single-institution experience and review of the literature. Ann Oncol. 1994. 5:909–913.