Journal List > Korean J Urol > v.48(1) > 1004915

Kim, Yang, and Chung: Recurrence Rate and Risk Factors for Stone Recurrence after Successful Extracorporeal Shock Wave Lithotripsy: 5-year-follow-up Study

Abstract

Purpose:

After treatment, urinary stones are known to have high recurrence rates. Therefore, the recurrence rates and risk factors for recurrence after successful extracorporeal shock wave lithotripsy (ESWL) were investigated to help in the decisions making for the treatment of patients with urinary stones.

Materials and Methods:

Between January 1999 and December 2000, 415 patients (444 renal units), treated by ESWL due to urinary stones, were followed up for 5 years using either KUB or sonography. Treatment success was defined as complete passage of the stone or insignificant stone fragments, less than 3mm in diameter, remaining. The stone recurrence rates were calculated using the Kaplan-Meier method. The possible risk factors for recurrence, such as sex, age, familial history of urinary stones, abnormal metabolic finding, pyuria after ESWL, stone location, size and multiplicity, were analyzed.

Results:

The overall number of recurrent stones was 82 in 444 renal units (18.5%). Using the Kaplan-Meier method, the recurrence rates were determined as 7.5, 17.8, 34.8, 39.8 and 45.8%, respectively, for each year upto 5 years. Among the many possible risk factors for a recurrence, the stone location (especially lower calyx) and multiplicity were found to be significant (p=0.042, p=0.009).

Conclusions:

Since the long term recurrence rates of the urinary stones can be as high as 45.8%, patients should be informed of this fact prior to treatment with ESWL. Especially, those patients with multiple or lower calyx stones should be followed-up more carefully. (Korean J Urol 2007; 48:49-53)

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Fig. 1.
(A) Stone location versus recurrence free rates. (B) Multiplicity versus recurrence free rates. ESWL: extracorporeal shock wave lithotripsy. statistically significant difference (p=0.042), f statistically significant difference (p=0.009).
kju-48-49f1.tif
Table 1A.
The characteristics of the 415 patients treated with ESWL
  No. of patients
Male/Female 256/159
Familial history of urinary stone
  Positive 46
  Negative 369
Age (years)
  0-<20 24
  20-<40 151
  40-<60 172
  60 ≤ 68
Abnormal metabolic finding (No.=238)
  Hypercalcemia 9
  Hypercalciuria 27
  Hhyperuricemia 21
  Hyperuricosuria 25
Pyuria after ESWL (No.=312)
  Positive 108
  Negative 204

ESWL: extracorporeal shock wave lithotripsy

Table 1B.
The characteristics of the original stones
  No. of renal units
Position
  Right 209
  Left 235
Location
  Kidney 142
   Calyx
    Upper 30
    Mid 38
    Lower 64
   Pelvis 10
   Ureter 302
    Upper 178
    Lower 124
Multiplicity
  Single 357
  Multiple 87
Size (mm)
  0-<10 272
  10-<20 93
  20-<30 68
  30 ≤ 11
Table 2.
Recurrence rates in years one to five after ESWL
Years after ESWL No. of recurrences (renal units) No. of overall recurrences (renal units) No. of stone free (renal units) Recurrence rate (%)
1 25 25 332 7.5
2 19 44 247 17.8
3 18 62 178 34.8
4 11 73 124 39.8
5 9 82 78 45.8

ESWL: extracorporeal shock wave lithotripsy

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