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Journal List > Korean J Urol > v.48(3) > 1004889

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Woo, Park, Kim, Kang, Jeong, and Yoo: Primary Bladder Signet Ring Cell Carcinoma Extended to Prostate
Case Report
Korean Journal of Urology

Korean Journal of Urology 2007; 48(3): 356-358.

Published online: 31 March 2007

DOI: https://doi.org/10.4111/kju.2007.48.3.356

Primary Bladder Signet Ring Cell Carcinoma Extended to Prostate

Je Hyeong Woo, Hyun Jung Park, Eun Kyung Kim1, Jeong Yoon Kang, Jeong Yun Jeong, Tag Keun Yoo

Department of Urology, Eulji University School of Medicine, Seoul, Korea.

1Department of Pathology, Eulji University School of Medicine, Seoul, Korea.

Corresponding author (ytk5202@eulji.or.kr)

Received 10 November 2006       Accepted 30 November 2006

Copyright © 2007 The Korean Urological Association

Abstract

A primary signet ring cell carcinoma (PSRCC) of the urinary bladder is a rare variant of a mucin-producing adenocarcinoma. The prognosis of a PSRCC is poor, as silent progression in a linitis platica fashion leads to delayed diagnosis. Herein, the case of a PSRCC of the bladder, which extended to the prostate, which was treated with a cystoprostatectomy, is reported.

Keywords: Carcinoma, signet ring cell, Bladder

Figures and Tables

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Fig. 1
(A) Prostatic urethral mass on cystoscopy. (B) Normal prostatic glands are seen on the left side, with dense tumor cells seen on the right side (H&E, ×100).

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Fig. 2
Post-transurethral resection (TUR) pelvic computer tomography showing multiple bladder wall thickening (A) and a filling defect of the left bladder base (B).

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Fig. 3
(A) Microscopic findings of a signet ring cell carcinoma. A histological examination revealed a predominance of cancer cells forming abundant mucin. Periodic acid-Schiff stain was positive (×400). (B) Prostate-specific antigen (PSA) stain showing no staining of the cancer cell (×100).

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