A Prostate Neoplasm Distantly Metastasized to the Unilateral Ureter

Deuk Jung Yong; Keon Cheol Lee; Jong Gu Kim; Mee Joo; In Rae Cho

doi:10.4111/kju.2007.48.3.352

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Yong, Lee, Kim, Joo, and Cho: A Prostate Neoplasm Distantly Metastasized to the Unilateral Ureter

Case Report

Korean Journal of Urology

Korean Journal of Urology 2007; 48(3): 352-355.

Published online: 31 March 2007

DOI: https://doi.org/10.4111/kju.2007.48.3.352

A Prostate Neoplasm Distantly Metastasized to the Unilateral Ureter

Deuk Jung Yong, Keon Cheol Lee, Jong Gu Kim, Mee Joo¹, In Rae Cho

Department of Urology, College of Medicine, Inje University, Busan, Korea.

¹Department of Pathology, College of Medicine, Inje University, Busan, Korea.

Corresponding author (ircho@ilsanpaik.ac.kr)

Received 9 October 2006 Accepted 31 January 2007

Abstract

Neoplasms of the prostate usually metastasize to pelvic lymph nodes or bone, or directly invade the adjacent pelvic organs. Ureteral metastasis of a prostatic carcinoma, without ascending spread along the ureter, is very rare, with only a few having been reported from autopsy series. Herein, the case of a prostatic carcinoma, distantly metastasized to the unilateral ureter, is reported.

Keywords: Prostatic neoplasms, Metastasis, Ureter

Figures and Tables

Fig. 1

(A) Retrograde ureteral pyelogram showing a 1cm sized irregular narrowing of the right lower ureter, with a uniformly dilated ureter above the point of obstruction. (B) Ureteroscopy showing no mass.

Fig. 2

Selective washing cytology showing medium-sized, round to oval, atypical cells.

Fig. 3

Abdomino-pelvic computed tomography (CT) scan (enhanced) showing a 1cm sized enhancing mass, with ill defined ureteral wall thickening at the right lower ureter.

Fig. 4

The distal ureter reveals a segmental luminal narrowing, with firm consistency, measuring 5.3cm in length. An encircling submucosal mass, with luminal constriction (white arrow), is present. The proximal ureter and pelvis are diffusely dilated.

Fig. 5

(A) Low magnification view demonstrating transmural infiltration of the tumor cells, but with a relatively intact mucosa (H&E, ×10 & ×40). (B, C) Tumor cells have hyperchromatic nuclei and scanty cytoplasm, accompanied with frequent squeezing artifact (H&E, ×100 & ×200). (D) Immunohistochemical staining of the prostate-specific antigen (PSA) showing diffuse and focal positivities.

References

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