Journal List > Korean J Urol > v.48(3) > 1004888

TOOLS
Yong, Lee, Kim, Joo, and Cho: A Prostate Neoplasm Distantly Metastasized to the Unilateral Ureter
Case Report
Korean Journal of Urology

Korean Journal of Urology 2007; 48(3): 352-355.

Published online: 31 March 2007

DOI: https://doi.org/10.4111/kju.2007.48.3.352

A Prostate Neoplasm Distantly Metastasized to the Unilateral Ureter

Deuk Jung Yong, Keon Cheol Lee, Jong Gu Kim, Mee Joo1, In Rae Cho

Department of Urology, College of Medicine, Inje University, Busan, Korea.

1Department of Pathology, College of Medicine, Inje University, Busan, Korea.

Corresponding author (ircho@ilsanpaik.ac.kr)

Received 9 October 2006       Accepted 31 January 2007

Copyright © 2007 The Korean Urological Association

Abstract

Neoplasms of the prostate usually metastasize to pelvic lymph nodes or bone, or directly invade the adjacent pelvic organs. Ureteral metastasis of a prostatic carcinoma, without ascending spread along the ureter, is very rare, with only a few having been reported from autopsy series. Herein, the case of a prostatic carcinoma, distantly metastasized to the unilateral ureter, is reported.

Keywords: Prostatic neoplasms, Metastasis, Ureter

Figures and Tables

Fig. 1
(A) Retrograde ureteral pyelogram showing a 1cm sized irregular narrowing of the right lower ureter, with a uniformly dilated ureter above the point of obstruction. (B) Ureteroscopy showing no mass.
kju-48-352-g001
Fig. 2
Selective washing cytology showing medium-sized, round to oval, atypical cells.
kju-48-352-g002
Fig. 3
Abdomino-pelvic computed tomography (CT) scan (enhanced) showing a 1cm sized enhancing mass, with ill defined ureteral wall thickening at the right lower ureter.
kju-48-352-g003
Fig. 4
The distal ureter reveals a segmental luminal narrowing, with firm consistency, measuring 5.3cm in length. An encircling submucosal mass, with luminal constriction (white arrow), is present. The proximal ureter and pelvis are diffusely dilated.
kju-48-352-g004
Fig. 5
(A) Low magnification view demonstrating transmural infiltration of the tumor cells, but with a relatively intact mucosa (H&E, ×10 & ×40). (B, C) Tumor cells have hyperchromatic nuclei and scanty cytoplasm, accompanied with frequent squeezing artifact (H&E, ×100 & ×200). (D) Immunohistochemical staining of the prostate-specific antigen (PSA) showing diffuse and focal positivities.
kju-48-352-g005

References

1. Stow B. Fibrolymphosarcoma of both ureters metastatic to a primary lymphosarcoma of the anterior mediastinum of thymus origin. Ann Surg. 1909. 1:901–906.
2. Higgins WH. Unusual ureteral extension of prostatic carcinoma. Bull Johns Hopkins Hosp. 1941. 68:337–346.
3. Marks LS, Gallo DA. Ureteral obstruction in the patient with prostatic carcinoma. Br J Urol. 1972. 44:411–416.
4. Schmidt SS. Prostatic carcinoma with direct extension to renal pelvis. Urology. 1974. 3:775–776.
5. Hulse CA, O'Neill TK. Adenocarcinoma of the prostate metastatic to the ureter with an associated ureteral stone. J Urol. 1989. 142:1312–1313.
6. MacLean JT, Fowler VB. Pathology of tumors of the renal pelvis and ureter. J Urol. 1956. 75:384–415.
7. Cohen WM, Freed SZ, Hasson J. Metastatic cancer to the ureter: a review of the literature and case presentations. J Urol. 1974. 112:188–189.
8. Kirschbaum H. Metastatic tumors of the ureter. J Urol. 1933. 30:665–678.
9. Campbell JE, Aldis HW. Lymphangitic ureteral metastases from prostatic carcinoma. J Can Assoc Radiol. 1980. 31:158–162.
10. Allsbrook WC Jr, Simms WW. Histochemistry of the prostate. Hum Pathol. 1992. 23:297–305.
TOOLS
Similar articles