Journal List > Korean J Urol > v.48(12) > 1004851

Lee, Moon, JI, Hwang, Choo, Kim, and Park: Solitary Fibrous Tumor as Misdiagnosed as Bladder Cancer

Abstract

Solitary fibrous tumor (SFT) was previously named localized fibrous mesothelioma, and this is a rare mesenchymal neoplasm that usually shows benign behavior. It is the most commonly recognized tumor of the pleura. These tumors have been recently reported to be found in unexpected locations. To the best of our knowledge, there have been only 2 reports of SFT arising from the urinary bladder in Koreans. We review this third case of SFT that was misdiagnosed as bladder cancer. This tumor was removed from a 40-year-old man who had a history of lower urinary tract symptoms.

Figures and Tables

Fig. 1
Preoperative transrectal ultrasonography revealed about a 3.6×3.4×3.7cm (25.9g) sized central protruding mass (A), and computerized tomography showed a round shaped intravesicular protruding mass that was probably due to prostatic gland enlargement (B). The round shaped solid mass showing partially hyperemic mucosa with a yellowish crust is observed in the left bladder trigone (C: intraoperative photograph). Photomicrography showed the characteristic "patternless pattern" of spindle cells with abundant collagenous deposition. On the immunohistochemical staining, the tumor cells showed diffuse, strong immunoreactivity for CD34 (D: H & E, reduced from ×400, E: reduced from ×400). Postoperative T2 weighted magnetic resonance imaging showed a 1.2×1.6×1.1cm sized residual solid mass in the intravesical mass (F).
kju-48-1319-g001

References

1. Weiss SW, Goldblum JR. Enzinger and Weiss's soft tissue tumors. 2001. 4th ed. St. Louis: Mosby;1021–1031.
2. Kim DS, Cha KB, Lee SR, Kim DJ, Cho NH, Choi YD. Solitary fibrous tumor of bladder. Korean J Urol. 2004. 45:393–395.
3. Lee JS, Hwa JS, Ko GH, Lee JH, Kim HW. Solitary fibrous tumor of the urinary bladder. Korean J Pathol. 2004. 38:129–131.
4. Westra WH, Grenko RT, Epstein J. Solitary fibrous tumor of the lower urinary tract: a report of five cases involving the seminal vesicles, urinary bladder, and prostate. Hum Pathol. 2000. 31:63–68.
5. Bainbridge TC, Singh RR, Mentzel T, Katenkamp D. Solitary fibrous tumor of urinary bladder: report of two cases. Hum Pathol. 1997. 28:1204–1206.
6. Lee MK, Shin DH, Cho MS, Kim YM, Kim J. Extrapleural solitary fibrous tumor-a clinical & pathological study of 8 cases. Korean J Pathol. 1999. 33:108–114.
7. Lee CJ, Jang BJ, Park HJ, Kim SY, Park HY. A case of localized fibrous tumor of pelvic cavity. Korean J Urol. 2001. 42:124–126.
8. Traweek ST, Kandalaft PL, Mehta P, Battifora H. The human hematopoietic progenitor cell antigen (CD34) in vascular neoplasia. Am J Clin Pathol. 1991. 96:25–31.
9. England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases. Am J Surg Pathol. 1989. 13:640–658.
TOOLS
Similar articles