Journal List > Korean J Urol > v.48(11) > 1004825

Cho, Hyun, Chung, Chang, and Han: Primary Leiomyosarcoma of the Ureter

Abstract

An 82-year-old woman was admitted to our hospital with a palpable mass in her right lower abdomen. The mass was enlarged and tender for the previous 3 months. Abdomen-pelvic computed tomographic scan demonstrated severe right hydroureteronephrosis and about an 8x8x9cm sized huge irregular shaped pelvic mass. Retrograde pyelography showed complete obstruction of the right middle ureter. En bloc resection of the mass and segmental resection of the ureter was performed. Pathologically, it was diagnosed primary leiomyosarcoma of the ureter. At 3 month postoperatively, there has been no recurrence or metastasis.

Figures and Tables

Fig. 1
Contrast enhanced computed tomographic scan shows delayed perfusion of the kidney and severe hydronephrosis, a hydroureter, (right (A)) and a huge irregular margined heterogeneous enhancing mass in the right pelvic cavity (B). The enhancing mass (empty arrow) seems to be of a retroperitoneal origin because the right ureter was compressed by the mass (C). Retrograde pyelography shows medial deviation and lower ureteral kinking and complete obstruction at the mid ureter (D).
kju-48-1174-g001
Fig. 2
The size of the large solid tumor was 10.5x10x7cm. Its shape and surface were irregular. On sections, it showed a white fibrotic solid appearance. The normal ureteral structure was not shown.
kju-48-1174-g002
Fig. 3
The tumor cells showed immunohistochemically positivety to actin (A) and desmin (B) It was composed of deeply eosinophilic intersecting fascicles (C) (H&E x40) and necrosis (D) (H&E x100). Mitotic figures (E) (H&E x200) were noted.
kju-48-1174-g003

References

1. Abeshouse BS. Primary benign and malignant tumors of the ureter: a review of the literature and report of one benign and twelve malignant tumors. Am J Surg. 1956. 91:237–271.
2. Hashimoto H, Tsuneyoshi M, Enjoji M. Malignant smooth muscle tumors of the retroperitoneum and mesentery: a clinicopathologic analysis of 44 cases. J Surg Oncol. 1985. 28:177–186.
3. Shirotake S, Sumitomo M, Asakuma J, Asano T, Aiko S, Hayakawa M. A case of primary leiomyosarcoma of the ureter. Hinyokika Kiyo. 2006. 52:41–45.
4. Griffin JH, Waters WB. Primary leiomyosarcoma of the ureter. J Surg Oncol. 1996. 62:148–152.
5. Raut CP, Pisters PW. Retroperitoneal sarcomas: combinedmodality treatment approaches. J Surg Oncol. 2006. 94:81–87.
6. Nakajima F, Terahata S, Hatano T, Nishida K. Primary leiomyosarcoma of the ureter. Urol Int. 1994. 53:166–168.
7. Moon DS, Kim HS, Park YI, Min BK. A case of retroperitoneal leiomyosarcoma. Korean J Urol. 1989. 30:430–433.
8. An HJ, Woo JW, Lee CK, Rhew HY. A case of retroperitoneal leiomyosarcoma. Korean J Urol. 1999. 40:526–528.
9. Gislason T, Arnarson OO. Primary ureteral leiomyosarcoma. Scand J Urol Nephrol. 1984. 18:253–254.
10. Rosenberg A. Cotran RS, Kumar V, Collins T, editors. Bones, joints, and soft tissue tumors. Pathologic basis of disease. 1999. 6th ed. Philadelphia: Saunders;1215–1268.
TOOLS
Similar articles