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Journal List > Korean J Urol > v.48(10) > 1004806

Yang, Kim, and Kim: A Preliminary Study of Troublesome Symptoms in Women with Acute Uncomplicated Cystitis

Abstract

Purpose

Although acute uncomplicated cystitis in women is relatively common, there have been few studies on lower urinary tract symptoms (LUTS) related to cystitis. The aim of this study was to assess characteristic troublesome symptoms in female patients with acute uncomplicated cystitis using a symptom questionnaire designed at our clinic.

Materials and Methods

An routine urinalysis and urine cultures were performed in 310 women who had visited our clinic between January 2005 and June 2006. Of these patients, 172 who had pyuria (mean age, 47.4±15.3 years) were screened for major symptoms using the questionnaire. The questionnaire included four categories of symptoms (14 symptoms): LUTS, local symptoms, general symptoms, and pain-related symptoms. The severity of symptoms was rated on a 4-point scale from 0 (no symptoms) to 3 (severe symptoms). The severity of symptoms was compared with the results of the routine urinalysis and urine cultures.

Results

Urine cultures were positive in 107 (62.2%) patients. Themost frequent and distressing symptom was dysuria, a pain-related symptom (89.0%, 1.78 points). Frequency was most common among LUTS (71.5%), and unwell was most common among the general symptoms (87.2%). In patients that were positive for urine cultures, the occurrence rate of low abdominal discomfort (81.3%, p=0.038) and irritability (72.9%, p=0.026) were significantly higher.

Conclusions

The questionnaire may be useful to assess duration and relief time of LUTS and to determine the progress and treatment outcomes of acute uncomplicated cystitis. Further studies will be required to investigate the effects of acute uncomplicated cystitis related to LUTS.

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Table 1.
Symptoms of the female patients with uncomplicated acute lower urinary tract infection
Symptoms Score %
LUTS
  Frequency 1.64 71.5
  Urgency 1.38 32.6
  Hematuria 1.66 42.4
  Tenesmus 1.70 11.6
Local symptoms
  Pressure in the genital area 1.20 33.7
  Low back pain 1.48 41.3
Generalized symptoms
  Unwell 1.41 81.2
  Weak, tiered or not in good form 1.27 63.7
  Irritable and restless in the body 1.56 66.3
  Felling hot 1.48 12.2
  Shivers, cold sweat without fever 1.28 14.5
  Nausea 1.55 6.4
Pain related symptoms
  Low abdominal discomfort 1.54 77.9
  Dysuria 1.78 89.0

LUTS: lower urinary tract symptoms

Table 2.
Symptoms of the female patients with uncomplicated acute lower urinary tract infection according to the urine culture results
Bacteriuria Positive Negative p-value
No. of patients Age 107 47.70±14.96 65 46.9±15.83 0.603
Symptoms Score % Score % p-value
LUTS
  Frequency 1.58 72.9 1.76 69.2 0.521
  Gross hematuria 1.66 42.4 1.64 33.8 0.078
  Tenesmus 1.29 13.1 1.00 9.2 0.231
Local symptoms
  Low back pain 1.32 43.9 1.38 36.9 0.696
Generalized symptoms
  Unwell 1.49 91.6 1.42 80.0 0.170
  Irritable and restless in the body 1.60 72.9 1.47 55.4 0.021
  Pain related symptoms
  Low abdominal discomfort 1.54 81.3 1.36 72.3 0.037
  Dysuria 1.78 93.5 1.77 81.5 0.094

LUTS: lower urinary tract symptoms

Table 3.
Incidence of symptoms of the female patients with an uncomplicated acute lower urinary tract infection according to age
Age (years) <35 36-50 51-65 >66 p-value
No. of patients 47 56 43 26
Symptoms (%)
LUTS
  Frequency 76.6 64.3 72.1 76.9 0.183
  Urgency 29.8 35.7 25.6 42.3 0.593
  Gross hematuria 42.6 46.4 44.2 30.8 0.420
  Tenesmus 17.0 10.7 9.3 7.7 0.196
Local symptoms
  Pressure in the genital area 25.5 44.6 30.2 30.8 0.898
  Low back pain 42.6 44.6 44.2 26.9 0.304
Generalized symptoms
  Unwell 87.2 89.3 90.7 76.9 0.391
  Weak, tired or not in good form 59.6 78.6 51.2 73.1 0.942
Pain related symptoms
  Low abdominal discomfort 80.9 80.4 72.1 76.9 0.432
  Dysuria 80.9 94.6 88.4 92.3 0.209

LUTS: lower urinary tract symptoms

Table 4.
Culture results of the female patients with an uncomplicated acute lower urinary tract infection
Cultured organism No. (%)
Escherichia coli 78 (72.9)
Gram positive rod 7 (6.5)
Klebsiella pneumonia 6 (5.6)
Group B Streptococcus 5 (4.7)
Enterococcus faecalis 4 (3.7)
Coagulase negative Staphylococcus 3 (2.8)
Proteus spp. 2 (1.9)
Others 2 (1.9)
Appendix.
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